-Context -The association between Helicobacter pylori infection and colon neoplasia has been the subject of recent investigations which have produced controversial results. Objective -To evaluate the prevalence of H. pylori infection in patients with colonic adenomas and also in patients whose colonoscopy exams were normal. Methods -After colonoscopy, the individuals were distributed into two groups: patients with colon adenomas (cases) and patients whose colons were normal (controls). The groups were similar regarding age and gender. The individuals of both groups were subjected to a dosage of IgG antibody against H. pylori. The dosage was applied according to the solid phase, chemiluminescent immunometric assay. The chi-square test was used to analyze the data. Results -There were 30 men and 64 women in each group (94 cases and 94 controls). The mean age of the cases was 59.79 ± 12.25 years and that of the controls was 58.98 ± 11.55 years. The H. pylori serology was positive for 66 (70.21%) of the cases and for 51 (54.25%) of the controls. There was a significant difference (P = 0.024). The odds ratio was 1.98 (CI 95%, 0.82-3.15). The prevalence of H. pylori in cases and controls according to gender, histological type and location of the colon lesions showed a significant difference only among women (P = 0.03), among patients with tubular adenomas (P = 0.03), and in those with distal adenomas (P = 0.038). Conclusion -There is a positive association between H. pylori infection and colonic adenomas. This association is more evident in women, especially for tubular adenomas and distal colonic location. HEADINGS -Helicobacter pylori. Adenoma. Colonic neoplasms. Helicobacter infections.
This study showed that the majority of cutaneosus horns occured in areas of the body that are exposed to the sun, predominantly head and upper limbs. Considering the high frequency of pre-malignant lesions and also the presence of malignant lesions it is suggested surgical exeresis followed by histopathological study of the cutaneous horns for confirmation of specific diagnosis.
e Priscila Meira VASCONCELOS 3 RESUMO -Contexto -O tromboembolismo venoso pós-operatório é uma entidade frequente e grave, que pode levar à embolia pulmonar e à síndrome pós-trombótica. Apesar dos benefícios comprovados pela profilaxia, nota-se uma inadequação na sua indicação. Objetivo -Verificar a indicação de heparina profilática entre pacientes de diferentes clínicas cirúrgicas de um hospital universitário de nível terciário. INTRODUÇÃOA trombose venosa profunda (TVP) e a embolia pulmonar (EP) são manifestações de um mesmo problema: o tromboembolismo venoso (TEV) (25) . Complicação da TVP, menos grave que a EP, é a insuficiência venosa crônica, também chamada síndrome pós-trombótica (14,15) . A dificuldade do diagnóstico da TVP, o retardo na terapêutica e a estreita relação entre TVP e EP determinam altas taxas de morbimortalidade (25) . No Brasil, provavelmente devido à falta de confirmação pela dificuldade de acesso aos serviços médicos e pela subnotificação, acredita-se que haja incidência de 0,6 caso/mil habitantes/ano (10) . Os pacientes politraumatizados ou os submetidos a intervenção cirúrgica de longa duração estão sob risco aumentado de desenvolver TEV. Esse risco aumenta com a idade, obesidade, em doentes com neoplasia, antecedentes cirúrgicos recentes e os estados trombogênicos. Além disso, há interferência de fatores individuais, tais como duração da intervenção, o tipo de anestesia, a imobilização pré e pós-operatória, o grau de hidratação e a presença de uma infecção (22) . Apesar de grandes evidências sobre a eficácia das medidas profiláticas para o TEV e de protocolos de prevenção da TVP estarem à disposição dos profissionais, existe expressiva variabilidade na prática médica, na aplicação dessas medidas. Diversos estudos
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