Background: Diabetes is associated with a high risk of cardiovascular diseases and underlying lipid abnormalities. Dyslipidemia, a modifiable risk factor is often underdiagnosed and undertreated in our patients. Its early identification can make aggressive cardiovascular preventive management possible. This report seeks to determine the prevelance and pattern of lipid abnormalities in type II diabetes mellitus. Methods: The lipid profiles and fasting blood sugar values of 100 known diabetics were studied. Their serum samples were assessed for fasting blood glucose [FBG], total cholesterol[TC], triacylglycerol [TG], low density lipoprotein cholesterol [LDL-C] and high density lipoprotein cholesterol [HDL-C] by using standard biochemical methods. Results: 83% of study subjects had lipid abnormalities. The mean TC, TG, LDL-C, and FBG levels were highly significant in the diabetics as compared to those in controls. It was found that 28% had hypercholesterolemia and 44% had hypertriglyceridemia. The mean HDL-C concentration was significantly high in female diabetics as compared to that in male diabetics. The correlation studies showed a nonsignificant negative correlation of FBG with TC, TG and LDL-C. Conclusion: In the diabetics higher frequencies of high TC, high TG and high LDL-C levels are noted indicating diabetic patients were more prone for dyslipidemia which could cause cardiovascular disorders.

No abstract

No abstract

Background: Diabetes is one of the widely occurring diseases acting as a threat to mankind. 65% of the diabetic deaths are due to cardiovascular complications therefore diabetes acts as a major risk factor for vascular diseases. Sedentary lifestyles followed by today's generation with unhealthy eating habits and obesity are the major risk factors for diabetes. The current study aims at evaluating the effect of lifestyle intervention on glucose regulation among individuals without glucose intolerance or diabetes. Methods: The study was conducted during a 3 month period. In this study the participants were randomly divided into control and intervention group. Data regarding age, weight, height was recorded from all. The candidates in the intervention group were taught about healthy eating habits, improving their physical activity etc. The follow up was done at an interval of 1 month and 3 month. Changes occurring in the baseline values were recorded. The data was analysed by SPSS software. Results: Out of 1039 candidates, 520 candidates were included in Group I and 519 candidates in Group II. Age, sex and height were similar amongst both the groups showing no significant difference. Mean systolic blood pressure, diastolic blood pressure, fasting blood sugar level were higher in control group compared to intervention group. The intervention group demonstrated a change in physical activity by 37.5 +/-8.2 hours/ week compared to 12.3+/-5.1 hours/week. The BMI amongst the intervention group demonstrated a mean decrease by 0.21 +/-0.1 whereas the control group showed an increase by 0.17 +//-0.2. The difference was not significant between the groups. Conclusion: Lifestyle interventions influence the risk factors associated with diabetes or various other diseases. Thus any alterations in risk factors can decrease or increase the chances of occurrence of the disease.

No abstract