This review summarizes the epidemiological trend, risk factors, prevention strategies such as vaccination, staging, current novel therapeutics, including the drugs under clinical trials, and future therapeutic trends for hepatocellular carcinoma (HCC). As HCC is the third most common cause of cancer-related death worldwide, its overall incidence remains alarmingly high in the developing world and is steadily rising across most of the developed and developing world. Over the past 15 years, the incidence of HCC has more than doubled and it increases with advancing age. Chronic infection with hepatitis B virus is the leading cause of HCC, closely followed by infection with hepatitis C virus. Other factors contributing to the development of HCC include alcohol abuse, tobacco smoking, and metabolic syndrome (including obesity, diabetes, and fatty liver disease). Treatment options have improved in the past few years, particularly with the approval of several molecular-targeted therapies. The researchers are actively pursuing novel therapeutic targets as well as predictive biomarker for treatment of HCC. Advances are being made in understanding the mechanisms underlying HCC, which in turn could lead to novel therapeutics. Nevertheless, there are many emerging agents still under clinical trials and yet to show promising results. Hence, future therapeutic options may include different combination of novel therapeutic interventions.
Background: Students choose their careers based on many factors, which vary for every country. Recent advancements in healthcare systems have made pharmacy one of the most pursued professions. Aim: To study the factors that influence students in Malaysia to choose pharmacy as their career. Methods: A cross-sectional study was conducted among first-year medicine, dentistry and pharmacy students in a private university in Malaysia. One-way analysis of variance followed by Tukey’s post-hoc test was used to determine the factors that influenced students’ career choices. Results: There were significant differences among medicine, dentistry and pharmacy students in the mean scores for the dimensions ‘economic status’, ‘personal background’, and ‘work-life balance’ which influenced their career choice. Conclusions: Economic status, personal background and work-life balance were the factors that significantly influenced students to choose pharmacy compared with students’ choice of dentistry and medicine.
BackgroundThe diabetes patients’ adherence to prescription medication is 67.5%, which is lower than that of patients with any other medical conditions. Patients with low medication adherence are more likely to experience clinical complications, repeated hospitalizations, increased mortality, and increased healthcare costs, hence, education on disease and medication adherence is vital now. This study aimed to assess the level of medication adherence, medicine and information-seeking behaviour, and the effectiveness of online educational intervention in improving medication adherence and medicine and information-seeking behaviours among patients with diabetes in Klang Valley, Malaysia.MethodsIndividuals aged 12 years and above with a prior diagnosis of diabetes were identified and randomly divided into (control (n=183), and intervention groups (n = 206). Data about their medication adherence and information-seeking behaviour were obtained. As part of the online educational intervention, a month of daily general reminders to take their medications and educational materials about diabetes had provided to them via WhatsApp groups. After a month, the groups were reassessed, and the data were compared.ResultsThe results showed that, at baseline, most of the respondents in the control (58.8% females and 53.08% males) and intervention (65.52% females and 85.12% males) groups had a low level of medication adherence. After a month of intervention, medication adherence was significantly improved in the intervention group (91.4% females and 71.28% males) compared to the control group (38.23% females and 44.44% males). At baseline, only 96 (52.45%) respondents in the control group and 110 (52.38%) in the intervention group preferred to read online educational materials to know more about their condition(s), it was improved after a month of intervention in the intervention group where 204 (99.02%) respondents prefer online materials, however no change in the control group response.ConclusionThe study concludes that medication adherence and information-seeking behaviours among the study population have been significantly improved after a month of structured intervention. Medication adherence plays a crucial role in risk reduction strategies subsequently it improves the patient’s quality of life. Thus, well-planned more robust educational interventions on chronic diseases are warranted to improve the health outcomes of the patients.
Objective: This paper describes the development and feasibility evaluation of a formative remote objective structured clinical examination (OSCE) for second-year students in a four-year Bachelor of Pharmacy (B.Pharm.) honours programme. Methods. A five- station remote formative OSCE was developed and implemented using Microsoft Teams. The authors used a post-OSCE evaluation, in combination with the results of a students’ survey and comprehensive feedback from faculty. Results: A total of seventy second-year B.Pharm. (Hons.) students participated in the online OSCE. Based on the post-OSCE evaluation, about 80% of students agreed that the OSCE ran smoothly. Respondents agreement on the time allocated to complete each station varied between 63.6% and 81.8%. Time allocation for each station and internet connectivity were raised as the main concerns by both the students and the faculty. Conclusion: A remote online OSCE is a feasible strategy for assessment of various skills based on different tasks, reflecting the scope of practice for future pharmacists, and offers a promising direction towards the assessment of such practical skills. Online OSCE planning, development and evaluation are in themselves useful for clarifying assessment goals, processes, hindrances, and affordances
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.