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<p class="abstract"><strong>Background:</strong> Novel coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thorough knowledge about its spread and symptoms, perceptions towards disease and practices to prevent its occurrence are essential. The goal of this study is to assess the knowledge, perceptions and practices of the Bangladeshi residents towards the COVID-19.</p><p class="abstract"><strong>Methods:</strong> A cross-sectional, web-based, pre-tested questionnaire was designed emphasized on the demographic profile, knowledge and perceptions about cause, transmission, prevention and cure of COVID-19. The questionnaires were distributed to 8 districts of Bangladesh only. The survey consists of close ended questions and took approximately 15 minutes to complete during the period of 20th March to 20th April 2020.  </p><p class="abstract"><strong>Results:</strong> A total of 320 completed the study questionnaire, including (67.5%) men and (32.5%) women, and most of them are age range 31-50 years (80.00%). 87.19% people knew cause of COVID-19 is viral and 48.75% knew it spreads through coughs. 77.81% people correctly knew about symptoms of COVID-19. 70.00% mentioned all the correct preventive methods as wearing face mask, vaccination, avoid mass gatherings and maintaining hand hygiene. In reality, only 40.00% people exclusively practicing hand hygiene. </p><strong>Conclusions:</strong> In general, Bangladeshi population participating in our survey had good knowledge about COVID-19, and a positive attitude towards using protective measures, which is important to limit the spread of the disease.

Background: The ongoing pandemic COVID-19 is a new disease that provides a little bit of knowledge. Modern society is getting further information about this pandemic. But the people who are far away from development may not get proper learning and instruction to defect the new virus. Keep this reality in mind, and we aimed via this study to find out the precipitance and knowledge about COVID-19 of the tribal community from Khagrachari district, who are backward and less developed people of Bangladesh.Methods: Simple random sampling method is used for selecting responders. A willing responder was interviewed using a per-developed questioner and 348 responders (Chakma-131, Marma-106 and Tripura-111) across the Khagrachari district. All statistical analyses were done by SPSS version 20.Results: COVID-19 is a viral disease known by 87.0% Chakma, 85.0% Marma and 81.1% Tripura alongside 54.2%, 53.8%, and 60.4% Chakma, Marma Tripura; respectively think that COVID-19 is a deadly disease. Using face masks as a safety measurement about 87% of Chakma, 85% of Marma, and 81.1% of Tripura but using hand sanitizer or shop was slightly low compared to facemask use. Although they were eager to take a vaccine at a particular time, it seems they are not optimistic about the vaccine's efficacy.Conclusions: Overall, the tribal population has sufficient knowledge about COVID-19 and has a good tendency to maintain proper health hygiene to prevent COVID19 infection.