In recent years, the transition‐metal‐catalyzed functionalization reactions of sulfoxonium ylides have been explored extensively because of their usefulness as carbene‐transfer agents, since they can produce metal carbenes through metal catalysis. Moreover, they are safer and have the advantages of simple handling and good stability over their other counterparts like diazo‐compounds. This review article attempts to highlight the recent advances in the metal‐catalyzed C−H functionalization of sulfoxonium ylides.
An
unprecedented annulation reaction is developed for the synthesis of
dihydrofuran-fused compounds. In this Ru-catalyzed hydroxyl-group-directed
reaction, easily affordable sulfoxonium ylides and 1,4-dioxane were
used as the annulating partners. This is the first example of the
use of 1,4-dioxane as a methylene source to construct a heterocyclic
scaffold. A wide range of dihydrofuran0fused coumarins and naphthalenes
were synthesized using this three-component reaction.
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