Background: Sinonasal mass is a common finding in the Otorhinolaryngology Department. These can be non-neoplastic or neoplastic. Nasal obstruction is the most common clinical presentation. Imaging studies are not always conclusive in these cases. So, the present study aimed at clinical presentation and histopathological classification of sinonasal masses.for histopathological examination and were stained by Hematoxylin and Eosin stain. Special stains were used wherever required. Immunohistochemistry was carried on cases with diagnostic difficulties. malignant tumours. Non-neoplastic lesions and benign tumours were commonly seen in middle age group while malignant tumours were seen in adult patients. Males were predominantly affected in non-neoplastic lesions and benign tumours. Malignant tumours showed female dominance. Nasal obstruction was the most common complaint. Overall, inflammatory nasal polyps were most common lesions. Inverted papillomas were most common benign tumours. Sinonasal undifferentiated carcinomas accounted for majority of malignant tumours. Conclusion:Sino-nasal masses or polyps can be non-neoplastic or neoplastic lesions and histopathological examination remains the mainstay in differentiating these lesions.
INTRODUCTIONBreast lump is the most common presentation of breast diseases. Although most of the cases of breast lump are benign it causes anxiety regarding possible malignancy. Preoperative diagnosis helps in planning the correct surgical and therapeutic treatment.Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed in 2012 and second most common cancer overall.1 Breast cancer is now the most common cancer in Indian women; having recently overtaken cervical cancer in this respect. 2Early diagnosis can improve the survival rate among breast cancer.The diagnostic process in breast cancer involves the "Triple test" consisting of clinical examination, mammography and fine needle aspiration cytology (FNAC).3 FNAC is a quick, simple, reliable and inexpensive procedure in diagnosing breast lumps. It is reported in different studies that FNAC have 80% to 98% sensitivity and more than 99% specificity. 4 The main purpose of fine needle aspiration cytology (FNAC) of breast lumps is to confirm cancer pre-operatively and to avoid surgery in specific benign conditions. The present study is designed to study utility of FNAC in diagnosis of breast lumps and to correlate cytological findings with histopathological findings. METHODSThis study was carried out in a tertiary care hospital providing medical services to the rural population. This was a retrospective study between January 2016 and December 2016. The study was approved by institution ethics committee. All the patients presenting with breast lump were included in the study. The patients were counselled about the procedure, informed consent was ABSTRACT Background: Breast cancer is the most common cancer in women worldwide. Fine needle aspiration cytology is a cost effective, easy procedure in the diagnosis of breast lump. Methods: This was a one year retrospective study between January 2016 and December 2016. Needle aspiration was done in 100 patients presenting with breast lump. Histopathology correlation was done in 33 cases. Results: Fibroadenoma were most common lesions. Malignancy was reported in 13 cases. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were found to be 85%, 100%, 100%, 96.3% and 97% respectively. Conclusions: Fine needle aspiration cytology is a simple, easy, OPD based, cost effective procedure with high sensitivity, specificity and accuracy in diagnosis of breast lumps.
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