Objective
To compare the neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), and platelet indices between women with pre‐eclampsia and normotensive pregnant women.
Methods
A cross‐sectional study conducted from January to July 2017 at a tertiary care hospital in Delhi, India. The study compared pregnant women aged 18–40 years with pre‐eclampsia diagnosed at term with healthy pregnant women matched for gestational age. Venous blood samples were drawn and complete blood count was analyzed. The parameters recorded were hemoglobin, red cell distribution width (RDW), platelet count, mean platelet volume (MPV), plateletcrit, and platelet distribution width.
Results
There were 67 women included in each group. NLR was higher in women with pre‐eclampsia compared with the control group (6.8 ± 7.6 vs 3.0 ± 0.98; P=0.001). Both PLR (14.18 ± 14.4 vs 9.54 ± 3.6; P=0.012) and MPV (9.45 ± 1.19 vs 9.02 ± 1.1; P=0.029) were higher in the study group compared with the control group. Platelet count was lower in pre‐eclamptic women compared with the control group (188 ± 89.7 vs 200.1 ± 62.36; P=0.014). RDW was also higher in the study group (P=0.025).
Conclusions
The present study found that the inflammatory markers NLR, PLR, RDW, and MPV were higher in women with pre‐eclampsia. Measuring NLR and PLR may be useful in predicting pre‐eclampsia among women at high risk during prenatal follow‐up.
Daily vitamins: A mild, general, and highly stereoselective Pd0‐catalyzed cascade to the triene system of the hormone 1α,25‐dihydroxyvitamin D3 and six representative analogues is reported. The intramolecular cyclization of an enol–triflate (lower fragment) followed in situ by Suzuki–Miyaura coupling with an alkenyl boronic ester (upper fragment, also efficiently prepared by Pd0‐catalyzed coupling) in equimolar amounts under protic conditions is ideal for the preparation of small amounts of new vitamin D analogues for biological testing (see scheme).
I2/surfactant/water system deprotecting oximes and imines to the corresponding carbonyl compounds under neutral conditions in water at 25-40 degrees C with very high to excellent yields.
CeO2 has been used as heterogeneous catalyst for carbon‐carbon bond formation via cross‐dehydrogenative coupling (CDC). It works efficiently for oxidative C−C bond formation between N‐aryltetrahydroisoquinoline derivatives and a carbon nucleophile nitroalkane and acetone under aerobic conditions. This is the first report of CeO2 as a low temperature catalyst for the carbon‐carbon bond formation reaction between two sp3 C−H bonds.
A novel heterogeneous catalytic hydrogenation-hydrogenolysis strategy has been developed for the α-methylation of ketones via enaminones using DMF dimethyl acetal as carbon source. This strategy provides a very convenient route to α-methylated ketones using a variety of ketones without any base or oxidant.
A facile and efficient procedure for the ipso‐hydroxylation of arylboronic acids to phenols in water was developed. A series of electron‐rich and electron‐deficient arylboronic acids were smoothly ipso‐hydroxylated with this protocol to afford products in excellent yields. Moreover, the protocol is amenable to boronate esters. In most cases, the phenolic products were obtained in pure form without any chromatographic purification.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.