Primary lymphoma of the breast is a rare occurrence because of the paucity of lymphoid tissue in the breast and is an even rarer entity in the male breast. Imaging, along with tissue diagnosis goes a long way in diagnosing breast lymphoma which has a significantly different management scheme than other breast neoplasms with respect to radio-chemotherapy rather than surgical resection. We present a case of primary male breast lymphoma which was evaluated with magnetic resonance imaging as well as other conventional imaging modalities and was treated by chemotherapy with a 7-month follow-up.
Objective: To investigate the incidence and spectrum of neuroimaging ndings and their prognostic role in hospitalized COVID-19 patients in Government Medical College Nagpur along with their correlation with D-Dimer Values and GCS . Methods: This is a retrospective cohort study of 774 COVID-19 conrmed patients admitted to Government Medical College st st Nagpur between 1 April 2020 and 31 October 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuro-radiologists evaluated all neuroimaging studies for acute neuroimaging ndings related to COVID-19. Plasma D-dimer levels were measured using a particle-enhanced, immunoturbidimetric assay on admission in the 116 patients who came for evaluation of neurological symptoms. Moreover ,the patients were classied into different groups as mild, moderate and severe based on their GCS scores and was assessed with respect to their neuro-imaging ndings. Results: 15 % of the admitted patients suffered from neurological symptoms. Acute stroke was the most common nding in the patients with positive neuroimaging ndings resulting in 34.4% of the patients with positive neuroimaging ndings. Other ndings were subacute infarcts (13.8%), Chronic lacunar infarcts (20.6%) , Intraparenchymal hemorrhage in 10.4 %, hypertensive encephalopathy in 7 % and subarachanoid hemorrhage in 3.4 %. Plasma median D-dimer levels were signicantly (P = 0.000) higher in Acute stroke patients as compared to COVID 19 positive patients who had negative CT scan imaging features(0.88; interquartile range [IQR], 0.28–2.11 mg/L and 0.31; IQR, 0.17–0.74 mg/L). Patients who have positive neuroimaging ndings presented with a lower GCS whereas patients who had negative neuroimaging ndings presented with a higher GCS. Conclusions: Our study demonstrates acute stroke is the most common neuroloimaging nding in hospitalized COVID 19 Patients. Moreover D-Dimer values are highly predictive of acute ischemic stroke. Patients with positive neuro-imaging ndings have poor GCS scores.
1. AIMS AND OBJECTIVES : Ÿ To determine the correlation between and predict the molecular subtypes of breast carcinoma based on mammography and ultrasound ndings. Ÿ To correlate the different epidemiological features of breast cancer patients with the molecular subtypes of breast carcinoma. 2. Materials And Methods: In our cross-sectional study, 84 biopsy proven cases of breast carcinoma were referred to radiology department. After taking informed consent and in presence of a female attendant, ultrasonography and mammography of the patients were done. All these patients went for surgical excision of the neoplastic mass; and the mass were sent for IHC analysis. Epidemiological data, clinical features, mammographic features and sonographic features were correlated with IHC subtype of the mass and P-Values were found out. P-Value<0.05 was considered to be statistically signicant. 3. Results: Ÿ Among 84 patients, 22 were of Triple Basal Negative subtype, 17 were of Luminal-A subtype, 16 were of Luminal-B (Her-2 negative) subtype, 15 were of Her-2 enriched subtype and 14 out of 84 patients were of Luminal-B (Her-2 positive) subtype. Ÿ IHC correlation between sex distribution, age distribution, age of menarche distribution, achievement of menopause and age of menopause distribution, parity distribution, history of breast feeding, family history of breast carcinoma, history of breast pain, breast ulceration, nipple discharge, quadrant location of breast mass and size of mass showed P-Value >0.05; which was statistically insignicant. Ÿ IHC corelation with mammographic microcalcications, shape of breast mass, margins of breast mass, posterior acoustic pattern of breast masses and vascularity of the breast mass showed P-Value <0.05; which was statistically signicant. 4. Conclusion: Mammographic microcalcication and other features on sonography like shape of the mass, margins of the mass, posterior acoustic features and vascularity of the mass are strongly correlated in predicting the molecular subtype of breast carcinoma.
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