Background: Skin is a complex ecosystem hosting a diverse microbial population as well as distinct environmental niches leading to hundreds of skin conditions that affect humans. There is an evident shift towards the metagenomic analysis from less efficient and strenuous culture-based techniques in biomedical research, thus creating a new dimension for dermatological study. A systematic and comprehensive study of skin microbiome appraises the dynamics between species, their interaction with the immune system, and composition in diseases. Research: Metagenomics include research techniques like next-generation sequencing, sequencing of ampliconbased assays, shotgun metagenomics, gene prediction, metatranscriptomics, and statistical and comparative studies allowing us to access the functional and metabolic diversity of the skin microbiome and their role in host health. In disorders like acne, dandruff, seborrheic dermatitis, and bovine digital dermatitis, metagenomics provides information about the organisms present conferring the condition, inter-microbial interactions, and expression profiles of communities. Conclusion: We have enriched our understanding of the uncultured world resulting in a better understanding of microbe interaction with each other and their host. Metagenomic analysis provides glimpses into topographical and interpersonal complexity that defines the skin microbiome. It has led to an advanced study of dermatological disorders like acne, dandruff, seborrheic dermatitis, atopic dermatitis, bovine digital dermatitis, and psoriasis, and this knowledge is a breakthrough in dermatology research for creating better therapeutic solutions and personalized treatments.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.