The prognostic significance of the six-minute walk distance for lower extremity events in people with peripheral artery disease (PAD) is unknown. This longitudinal study assessed whether a poorer six-minute walk distance at baseline was associated with higher rates of subsequent lower extremity atherosclerotic disease events in PAD. A total of 369 patients (mean age 69.4 ± 10.0 years; mean ankle–brachial index (ABI) 0.67 ± 0.17; 31% women; 30% black individuals) from Chicago-area medical centers with PAD were enrolled. Participants underwent baseline six-minute walk testing and returned for annual study visits. Lower extremity events consisted of one or more of the following: ABI decline greater than 15% or medical record adjudicated lower extremity revascularization, critical limb ischemia, or amputation. At a mean follow-up of 33.3 months, lower extremity events occurred in 66/123 (53.7%) people in the first (worst) tertile of six-minute walk performance, 55/124 (44.4%) in the second tertile, and 56/122 (45.9%) in the third (best) tertile. After adjusting for age, sex, race, ABI, comorbidities, and other confounders, participants in the first (worst) tertile of six-minute walk distance at baseline had higher rates of lower extremity events during follow-up, compared to those in the best tertile at baseline (HR = 1.74, 95% CI 1.17–2.60, p = 0.0067). Among people with PAD, a poorer six-minute walk distance was associated with higher rates of subsequent lower extremity PAD-related events after adjusting for confounders. Further study is needed to determine whether interventions that improve six-minute walk distance can reduce lower extremity adverse events in people with PAD.
Aims: Assessment of risk factors and the role of habit variables such as duration and frequency in the severity of OSMF and to ascertain the association of gender predilection for different habits and severity of OSMF. Study Design: Descriptive retrospective study. Place and Duration of Study: Department of Oral Medicine and Radiology, Rural Dental College, Pravara Institute of Medical Sciences (Deemed University), Loni Bk. between January 2012 and December 2019. Methodology: This descriptive retrospective study of 1790 OSMF patients was carried out at the tertiary level dental hospital in the rural population of Western Maharashtra. The clinicodemographic data including details of habits was collected for a period of 8 years. Results: The average age of the patient in the study was 32.8 years, with 16.5:1 M:F ratio. Significantly higher proportions of females (69.6%) were illiterate and belonged to low socioeconomic status.There was a statistically significant increase for areca nut chewing (OR=0.135(0.054-0.342), P < 0.0001), gutkha chewing (OR=22.32(10.421-47.817), P < 0.0001), tobacco chewing (OR= 0.111(0.04-0.308), p<0.0001), smoking habits (OR=30.791(7.472-126.89), P < 0.0001) and alcohol (OR=12.692(3.077-52.347, p < 0.0001) in males when compared with females.The maximum patients were seen in stage II (37%) and stage III (34%), followed by stage I (18.73%) and stage IV (10.3%) and the severity of OSMF was more in subjects who had the habits for longer duration. Conclusion: There was a definite gender predilection for various habits and their variables (frequency, duration), educational and socioeconomic status, clinical features and disease severity. Significant correlation was also found between habit variables (duration, frequency) and severity of the disease.
<p class="abstract"><strong>Background:</strong> Aero-digestive foreign bodies are prevalent in our part of the country. Apart from the usual foreign body we encountered some unique foreign bodies, the diagnosis and management of which, is difficult due to varied and overlapping clinical presentation. Rare foreign bodies in the aero-digestive tract pose challenges in diagnosis and treatment.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective observational study on thirty patients with aerodigestive foreign bodies who visited our hospital from July 2015 to October 2017. </p><p class="abstract"><strong>Results:</strong> Maximum number of cases was seen in age group of 0-5 years. The male to female ratio was 2:1. Among various types of foreign bodies, majority were metallic (43.3%). The most common site was cricopharynx (53.3%) followed by bronchus (26.6%) and esophageal (16.6%). The most common procedure done was hypopharyngoscopy (53.3%).</p><p class="abstract"><strong>Conclusions:</strong> Aerodigestive tract foreign bodies are one of the emergencies that have considerable mortality and morbidity. High degree of skill and suspicion are required by surgeon for the management of foreign body.</p>
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.