These results can aid in restructuring the municipality's pharmaceutical services because they underscore the need to improve and to increase rational drug use as a therapeutic resource imperative to supporting health efforts.

Introduction: Brazilian epidemiological studies on systemic lupus erythematosus (SLE) are scarce, and currently available data originate almost entirely from international literature. Objectives: To determine the incidence and some clinical and laboratory characteristics of patients with SLE in the municipality of Cascavel, state of Paraná, Brazil. Patients and Methods: Data were collected from August 2007 to July 2008 in all health services of Cascavel providing health care in rheumatology: a university-affi liated hospital, a public outpatient clinic, and three private clinics. Results: The study identifi ed 14 patients diagnosed with SLE, which resulted in an estimated incidence of 4.8 cases/100,000 inhabitants/ year. All patients were female, and the mean age was 41.5 years. The highest incidence of disease occurred between 30 and 39 years of age, and 92.8% of patients met at least four of the 11 American College of Rheumatology (ACR) criteria for diagnosis of SLE. The drug treatment of patients was also assessed and proved to be in accordance with the Brazilian Consensus for Treatment of SLE. Conclusion: The incidence obtained in the municipality of Cascavel is close to those reported in international studies.

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The consumption of alcohol and illicit substances has shown alarming levels among young university students, and its use may be associated with the coping strategy of academic burnout. This review aimed to synthesize the scientific evidence related to the consumption of alcohol and illicit substances associated with burnout syndrome in university students. Searches were carried out in: Biblioteca Virtual em Saúde, PubMed, Web of Science, PsycNet and Scopus databases, with no year limitation and based on the PRISMA guideline. Among the 2.269 articles identified, 16 met the inclusion criteria. All studies evaluated students in the health area, 12 studies found an association between the variables, with alcohol and illicit substances consumption strongly related to burnout syndrome. It was concluded that there is an association between the studied variables, indicating that the presence of burnout syndrome in university students can result in the use of negative strategies as a coping measure.

Propõe-se com o presente estudo, descrever a evolução das ações da atenção primária em saúde e correlaciona-las às hospitalizações por condições sensíveis a esse nível de atenção. Trata-se de um estudo ecológico, retrospectivo e analítico, a partir de dados secundários. Foram objetos de estudo a abrangência populacional das eSF, PACS e número de NASF, além das internações por condições sensíveis a atenção primária, no Paraná e suas cinco maiores cidades. Utilizou-se o modelo de correlação de Pearson, a fim de investigar a relação entre as variáveis.  Observou-se tendência crescente na abrangência das eSF em todos os locais do estudo. Houve decréscimo importante no número de ICSAP no período estudado, bem como correlação estatística negativa com o a ampliação da cobertura das ações da APS no estado do Paraná.