The venous and arterial thromboembolic disorders are still be the major cause of morbidity and mortality worldwide. Now a days, the concept of "healthy diets" is very popular in the present lifestyle. So, the use of antithrombotic agents is of considerable interest in the role of natural food products and their bioactive components in the prevention and treatment of these disorders. Moreover, epidemiologic studies have provided evidence that foods with the thrombolytic/fibrinolytic effect could reduce the risk of thrombosis. "Blood thinner foods" have the antiplatelet, anticoagulant, and/or fibrinolytic properties. Natural foods that contain salicylates can mimic some of the antiplatelet effects of cardiovascular drug like aspirin. Fruits (i.e., grapefruit, guava, kiwi, pineapple, and watermelon), vegetables (i.e., alfalfa, beans, corn, potato, radish, and zucchini), and spices (i.e., chili, curry, ginger, rosemary and turmeric) are reported that they are containing salicylates compounds. Turmeric (Curcuma longa) is a small rhizomatous perennial herb belonging to Zingiberaceae family originating from Southeastern Asia. It is a folk remedy for applying on fresh cuts to stop bleeding and for the healing of wound. Further, turmeric has been shown to possess anticancer, antidiabetic, antifertility, anti-inflammatory, antimicrobial and antioxidant properties. Its phytochemical substances are alkaloids, curcuminoids, flavonoids, glycosides, saponins, which all of these contribute to its remedial properties. This article provides a brief overview of the antithrombotic activity of turmeric, C. longa to further provide an up-to-date review showing its importance.
Ipomoea reniformis Chaos is claimed in Indian traditional medical practice to be useful in the treatment of epilepsy and neurological disorders. In the present study, pretreatment effect of methanolic extract of Ipomoea reniformis on epilepsy and psychosis was evaluated in rodents using standard procedures. Besides evaluating epileptic and behavioral parameters, neurotransmitters such as Gamma-Amino Butyric Acid (GABA) in epilepsy and in psychosis dopamine, noradrenaline and serotonin contents in the rodent brain were estimated. The extract pretreatment reduced maximal electro shock; Isoniazid (INH) and Pentylenetetrazole (PTZ) induced seizures and also significantly inhibited the attenuation of brain GABA levels by INH and PTZ in mice. These results suggested that the observed beneficial effect in epilepsy may be by enhancing the GABAergic system. The test drug also inhibited the apomorphine induced climbing and stereotyped behavior and showed significantly reduced levels of brain dopamine, noradrenaline and serotonin which may be due to blocking of central dopaminergic, noradrenergic and serotonergic pathways or by enhancing the GABAergic system. The results obtained in present study suggest that the title plant possesses antiepileptic and antipsychotic activities in rodents.
Bacopa monnieri, Family: Plantaginaceae, known as water hyssop, herb of grace or Indian penny wort, is one of the traditional medicinal plants in Ayurveda medicine, where it is also called Brahmi, a name derived from Brahma, the creator God of the Hindu Pantheon. It is now being widely promoted to enhance memory, learning and concentration and also to treat anxiety, depression, and systemic disorders like cardiovascular, gastrointestinal, hepatic, neurological and also respiratory problems. Further, Brahmi has been shown to possess anticancer, antidiabetic, anti-inflammatory, antimicrobial and antioxidant properties. Its phytochemical substances are alkaloids, flavonoids, glycosides, saponins, and the important constituents such as bacosides, bacopasides, and bacopasaponins, which all of these contribute to its remedial properties. This article provides a brief overview of the memory boosting activity of brahmi, (B. monnieri), to further provide an upto-date review showing its importance especially, memory boosting.
The efficacy of Endocrine Disrupting Compounds (EDCs), 17β-estradiol was tested on the fish Oreochromis niloticus in order to understand the intersex relationship of fish, in which sequential hermaphrodism can consist of a male changing into a female (protandry) or a female changing into a male (protogyny). The fish were equally divided into 3 groups. The first group was the control group; the second and third groups were treated with 10 and 100 g L -1 of 17β-estradiol, respectively, for 30 days. The overall result in this experiment had no significant effect on the growth parameters. Among the two treated groups, the low concentration group shows results similar to those of the control groups. The high concentration group shows changes to the male reproductive system with the appearance of the testis-ova present resulting in an intersex condition of the male gonads. With this experiment, it can be concluded that 17β-estradiol at high concentration reveals positive changes towards the male reproductive system of the fish, Oreochromis niloticus.
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