Background: Contemporarily, cardiac arrest (CA) remains one of the leading causes of death. Poor nutritional status can increase the post-CA mortality risk. The aim of this study was to determine the relationship between body mass index (BMI) and Nutritional Risk Score 2002 (NRS 2002) results and in-hospital mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest. Methods: A retrospective study and analysis of medical records of 161 patients admitted to the ICU of the University Clinical Hospital in Wrocław (Wrocław, Poland) was conducted. Results: No significant differences in body mass index (BMI) and nutritional risk score (NRS 2002) values were observed between non-survivors and survivors. Non-survivors had significantly lower albumin concentration (p = 0.017) and total cholesterol (TC) (p = 0.015). In multivariate analysis BMI and NRS 2002 scores were not, per se, associated with the in-hospital mortality defined as the odds of death (Model 1: p: 0.700, 0.430; Model 2: p: 0.576, 0.599). Univariate analysis revealed significant associations between the hazard ratio (HR) and TG (p ≈ 0.017, HR: 0.23) and hsCRP (p ≈ 0.018, HR: 0.34). In multivariate analysis, mortality risk over time was influenced by higher scores in parameters such as BMI (HR = 0.164; p = 0.048) and hsCRP (HR = 1.006, p = 0.002). Conclusions: BMI and NRS 2002, on their own (unconditionally – in the whole study group) did not alter the odds of mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest. The risk of in-hospital mortality (expressed as hazard ratio – the risk over the time period of the study) increased with an increase in BMI but not with NRS 2002.
Introduction: Ankylosing spondylitis (AS) is a chronic, progressive disease, often with multiple complications, with periods of exacerbation and remission. The onset of the disease usually affects people under 30 years of age. The disease impairs physical, psychological, and social functioning, leading to disability. Therefore, patients with AS face the challenge of adapting to life with the condition and deteriorating quality of life (QoL).Objective: This study aimed to assess the impact of disease acceptance on quality of life in patients with AS. Material and Methods:The study was conducted in the Department of Rheumatology and Internal Diseases of the University Hospital in Wrocław among 110 patients (67 men and 43 women) with the diagnosis of AS, aged 20-89 years (M=48.44 years, SD ±12.55). The study used the Acceptance of Illness Scale (AIS), the WHOQoL-BREF Quality of Life Scale, and a self-constructed questionnaire of clinical and sociodemographic data. Results: Respondents rated the quality of life as good and moderate (M = 3.49 points, SD=±0.84). The mean AIS score was 27.44 (SD=±8.67). AIS scores are positively correlated with all QoL domains and perception of quality of life and health (p<0.001). The strongest correlation was in the physical domain (r=0.71), while the weakest correlation was observed in the social domain (r=0.329). AIS and QoL measures showed significant relationships with selected sociodemographic data (eg, gender, age, education, and occupational activity) and correlated with selected disease data (eg, type of treatment used, duration of disease, or comorbidities). Conclusion: AIS in patients with AS condition correlated positively with their QoL in all domains. Both disease acceptance and quality of life are influenced by specific sociodemographic and disease-related data. Prevention of complications and the type of treatment for AS (primarily biological treatment) can be essential in improving patients' quality of life.
Funding Acknowledgements Type of funding sources: None. Introduction Sudden cardiac arrest (SCA) is still one of the leading causes of death. Obesity can increase the risk of post-SCA mortality. The aim of this study was to retrospectively analyze the differences between non-obese and obese patients admitted to the intensive care unit (ICU) after out and in-hospital cardiac arrest. Material and Method A retrospective study and analysis of 161 medical records of patients admitted for SCA to the ICU (in an university clinical hospital in Poland) was conducted. Patient comorbidity, and laboratory results were collected. The study was approved by the independent Bioethics Committee of Wrocław Medical University No. KB-776/2022. Statistical analysis was performed with Python 3.9.13. Result The median age of obese patients was 71 years old and of non-obese 65 years old (p = 0.039).The sample population was divided into groups: according to WHO criteria. Differences between non-obese and obese patients in survivors group are shown Table 1. Significant differences in frequency were observed for cerebral stroke (CS) and diabetes mellitus (DM). Differences between non-obese and obese patients in non-survivors group are shown Table 2. Significant differences in frequency were observed for chronic kidney disease (CKD), DM, and hypertension (HT) Conclusion Among obese patients after cardiac arrest, the odds of comorbidities are higher. The research and medical community, should take up this challenge head-on and work harder on addressing the preventive and curative components of Non-Communicable Diseases.Survivors: obese vs obeseNon-survivors: obese vs obese
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