Herein, we report a palladium/norbornene/copper co-catalyzed single-step approach that merges selective ortho CÀ H bond esterification with ipso thiolation for construction of synthetically versatile 2-arylthio aryl esters under exceptionally mild conditions. Importantly, this process proceeded in a highly efficient manner, allowing alkoxycarbonyl and thio groups to be installed into one aryl iodides simultaneously by harnessing thiocarbonate as bifunctional reagent. The method has been demonstrated to accommodate good functionalities and features broad substrate scope.
Herein, we reported a transition-metal-free three-component
trifluoromethyl heteroarylation of vinyl ethers under visible light
irradiation. This protocol proceeded through a radical addition/cyclization
sequence which hinged on the intrinsic nucleo/electrophilic reactivity
of both the radicals, alkene, and alkynones, allowing β-trifluoromethyl
alkyl thiochromones furnished with high efficiency and excellent functional
group tolerance. By virtue of this procedure, three distinct chemical
bonds including C(sp2)–C(sp3), C(sp3)–C(sp3), and C(sp2)–S
have been successively forged in a single pot.
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