Twenty-seven com pounds in clud ing eight long-chain hy dro car bons, 1-hexacosanol (1), 1-octacosanol (2), palmitic acid (3), stearic acid (4), oleic acid (5), linoleic acid (6), heptacosyl eicosanate (7), glyceryl--tetraeicosanoate (8); three ster ols, -sitosterol (24), stigmasterol (25), -sitosteryl-3-O-D-glucopyranoside (26); one triterpene, lupeol (27); eight anthraquinones, chrysophanol (9), emodin (10), physcion (11), citreorosein (12), rhein (13), rhein methyl es ter (14), ziganein (15), 1,4,5-trihydroxyanthraquinone (16); two coumarins, isoscopoletin (17), scopoletin (18); two chromones, 2,5-dimethyl-7-hydroxychromone (19), 2,5-dimethyl-7-methoxychromone (20); three ar o matic com pounds, isovanillic acid (21), vanillic acid (22), and 2,4-dihydroxybenzaldehyde (23), were iso lated and iden ti fied from the bark of Cassia fis tula. Their structures were de ter mined on the ba sis of spec tral data. IN TRO DUC TIONCassia fis tula L (Leguminosae) is widely dis trib uted in In dia, the Phil ip pines, South China and Tai wan. It has long been used as folk med i cine to treat gas tri tis and make in sec ticide. 1 Chem i cal com po nents of this plant have been ex tensively in ves ti gated; flavanoids, oxyanthraquinones, sug ars, and triterpenoids have been re ported from its leaves, flow ers, trunk, and fruit. 2-6 Be cause of the in ter est on the ac tive compo nents of anthraquinones, we have in ves ti gated the aril of this spe cies, and found twenty-seven com pounds in clud ing eight anthraquinones, eight long-chain hy dro car bons, four ster ols, one triterpene, two coumarins, two chromones, three ar o matic com pounds, and five sug ars. In this pa per, we reported the iso la tion and char ac ter iza tion of chem i cal con stitu ents from its arils. RE SULTS AND DIS CUS SIONThe methanolic ex tracts of dried aril of C. fis tula L. were con cen trated to ob tain res i due and it was par ti tioned between CHCl 3 and H 2 O. The aque ous layer was sub se quently ex tracted with n-BuOH. CHCl3 and n-BuOH lay ers were concen trated and then sub jected to chro ma tog ra phy. They allowed the iso la tion of 1-hexacosanol ( 1), 7 1-octacosanol (2), 7 palmitic acid (3), stearic acid (4), oleic acid (5), 8 linoleic acid (6), 9 heptacosyl eicosanate (7), 10 chrysophanol (9), 11 phys cion (11 ), 12 rhein methyl es ter (14), 13 ziganein (15), 14 -sitosterol (24), 15 stigmasterol (25), 15 lupeol (27) 8 from the CHCl3 sol u -2,5-dimethyl-7-meth oxy chromone (20), 21 vanillic acid (22), 23 2,4-dihydroxybenzaldehyde (23), 24 glyceryl-1-tetracosanoate (8), 25 -sitosterol-D-glucoside (26), 9 from the n-BuOH sol u ble frac tion, The struc tures of these com pounds were de ter mined on the ba sis of spec tral data, chem i cal derivatization and com par i son with au then tic sam ples.The char ac ter is tics of anthraquinones are the col ored solid state (yel low to red) and the ap pear ance of C-1, -4, -5, or -8 hydroxyl group sig nal at H ~12 (hy dro gen bond ing). Com pound 14 was re ported ear lier by Henneberg, 17 but the phy...
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