Finally, one of the minor products (3.9%) was identified as epoxy precocene I1 based on its R, values in 4:l ether-hexane (0.85) and 93:7 benzeneethyl acetate (0.41), its GC retelition time, and its mass spectrum which was identical with 3,4-epoxy-6,7-dimethoxy-2,2-dimethylchtoman. At this time, it is not known whether epoxy precocene I1 serves as an ilitermediate in the formation of precocene I1 diol, but it is certainly a possible metabolic pathway.All of the synthetic metabolites were bioassayed for antijuvenile hormone activity using the milkweed bug as the test organism (Bowers et al., 1976). However, none of the compounds were active. ACKNOWLEDGMENT We thank C. W. Hessney for technical assistance.
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