The results of our study showed both a worrying percentage of strains of Salmonella Enteritidis resistant to nalidixic acid and of strains of Salmonella Typhimurium with a pattern of resistance to four antibiotics or more. Surveillance of antimicrobial resistance should carry on and improve in order to be able to evaluate the control measures carried out for decreasing resistance in Salmonella, specifically that addressed to the prudent use of antimicrobial agents by farmers and veterinarians.
We analyzed the Spanish hospital discharges registered from 1997 to 2005 with patient diagnoses of "intestinal infection due to Clostridium difficile." The mean annual incidence rate was 41.2 diagnoses per 100,000 discharges. A significant increase was found from 1997 to 2005 (slope of the regression line [b], 5.12; P < .001). Overall rates were 2.5 times as high in the group of patients aged at least 65 years as in the group aged 45-64 years.
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