A high throughput test which is based on a micromachined mixer for molecular gas-liquid reactions was evaluated for the kinetic investigation of the asymmetric hydrogenation of methyl Z-(a)-acetamidocinamate with a rhodium/(S,S-BDPPTS) catalyst in an aqueous phase. Up to 214 tests were performed in a short time and with an average inventory of Rh/test as low as 14 mg. Comparisons with traditional batch experiments are provided.
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