Effects of mercury (Hg) on birds have been studied extensively and with increasing frequency in recent years. The authors conducted a comprehensive review of methylmercury (MeHg) effects on bird reproduction, evaluating laboratory and field studies in which observed effects could be attributed primarily to Hg. The review focuses on exposures via diet and maternal transfer in which observed effects (or lack thereof) were reported relative to Hg concentrations in diet, eggs, or adult blood. Applicable data were identified for 23 species. From this data set, the authors identified ranges of toxicity reference values suitable for risk-assessment applications. Typical ranges of Hg effect thresholds are approximately 0.2 mg/kg to >1.4 mg/kg in diet, 0.05 mg/kg/d to 0.5 mg/kg/d on a dose basis, 0.6 mg/kg to 2.7 mg/kg in eggs, and 2.1 mg/kg to >6.7 mg/kg in parental blood (all concentrations on a wet wt basis). For Hg in avian blood, the review represents the first broad compilation of relevant toxicity data. For dietary exposures, the current data support TRVs that are greater than older, commonly used TRVs. The older diet-based TRVs incorporate conservative assumptions and uncertainty factors that are no longer justified, although they generally were appropriate when originally derived, because of past data limitations. The egg-based TRVs identified from the review are more similar to other previously derived TRVs but have been updated to incorporate new information from recent studies. While important research needs remain, a key recommendation is that species not yet tested for MeHg toxicity should be evaluated using toxicity data from tested species with similar body weights. Environ Toxicol Chem 2017;36:294-319. # 2016 SETAC
Cause-effect sediment-quality benchmarks for the protection of benthic invertebrates are needed for polychlorinated biphenyls (PCBs) to support predictive risk assessments and retrospective evaluations of the causes of observed sediment toxicity. An in-depth evaluation of PCB aquatic toxicity and organic carbon partitioning was conducted to predict sediment effect concentrations using the equilibrium partitioning (EqP) approach. This evaluation was limited to invertebrate toxicity data, because PCBs may exert toxicity to invertebrates and fish via different toxicological mechanisms. As a result of differences in organic carbon partitioning among PCBs of differing levels of chlorination, the estimated EqP benchmarks increase with increasing degree of chlorination for various commercial and environmental PCB mixtures. Studies of spiked sediment toxicity using PCBs were reviewed, and their results generally were consistent with EqP predictions. Additionally, toxicity and benthic community data were reviewed for eight PCB-contaminated sites; these data also showed agreement with EqP predictions. None of these lines of evidence supports previously proposed, empirical sediment-quality guidelines for PCBs. Reasons for the lack of agreement between cause-effect and association-based benchmarks are discussed, and areas of future research to further refine EqP predictions for PCBs are identified.
Triclosan, an antimicrobial compound used in personal care products, occurs in the aquatic environment due to residual concentrations in municipal wastewater treatment effluent. We evaluate triclosan-related risks to the aquatic environment, for aquatic and sediment-dwelling organisms and for aquatic-feeding wildlife, based on measured and modeled exposure concentrations. Triclosan concentrations in surface water, sediment, and biota tissue are predicted using a fugacity model parameterized to run probabilistically, to supplement the limited available measurements of triclosan in sediment and tissue. Aquatic toxicity is evaluated based on a species sensitivity distribution, which is extrapolated to sediment and tissues assuming equilibrium partitioning. A probabilistic wildlife exposure model is also used, and estimated doses are compared with wildlife toxicity benchmarks identified from a review of published and proprietary studies. The 95th percentiles of measured and modeled triclosan concentrations in surface water, sediment, and biota tissues are consistently below the 5th percentile of the respective species sensitivity distributions, indicating that, under most scenarios, adverse affects due to triclosan are unlikely.
The fate and partitioning of the antimicrobial compound, triclosan, in wastewater treatment plants (WWTPs) is evaluated using a probabilistic fugacity model to predict the range of triclosan concentrations in effluent and secondary biosolids. The WWTP model predicts 84% to 92% triclosan removal, which is within the range of measured removal efficiencies (typically 70% to 98%). Triclosan is predominantly removed by sorption and subsequent settling of organic particulates during primary treatment and by aerobic biodegradation during secondary treatment. Median modeled removal efficiency due to sorption is 40% for all treatment phases and 31% in the primary treatment phase. Median modeled removal efficiency due to biodegradation is 48% for all treatment phases and 44% in the secondary treatment phase. Important factors contributing to variation in predicted triclosan concentrations in effluent and biosolids include influent concentrations, solids concentrations in settling tanks, and factors related to solids retention time. Measured triclosan concentrations in biosolids and non-United States (US) effluent are consistent with model predictions. However, median concentrations in US effluent are over-predicted with this model, suggesting that differences in some aspect of treatment practices not incorporated in the model (e.g., disinfection methods) may affect triclosan removal from effluent. Model applications include predicting changes in environmental loadings associated with new triclosan applications and supporting risk analyses for biosolids-amended land and effluent receiving waters.
Triclosan is an antimicrobial compound found in many consumer products including soaps and personal care products. Most triclosan is disposed of down household drains, whereupon it is conveyed to wastewater treatment plants. Although a high percentage of triclosan biodegrades during wastewater treatment, most of the remainder is adsorbed to sludge, which may ultimately be applied to land as biosolids. We evaluated terrestrial ecological risks related to triclosan in land-applied biosolids for soil microbes, plants, soil invertebrates, mammals, and birds. Exposures are estimated using a probabilistic fugacity-based model. Triclosan concentrations in biosolids and reported biosolids application rates are compiled to support estimation of triclosan concentrations in soil. Concentrations in biota tissue are estimated using an equilibrium partitioning model for plants and worms and a steady-state model for small mammals; the resulting tissue concentrations are used to model mammalian and avian dietary exposures. Toxicity benchmarks are identified from a review of published and proprietary studies. The results indicate that adverse effects related to soil fertility (i.e., disruption of nitrogen cycling) would be expected only under "worst-case" exposures, under certain soil conditions and would likely be transient. The available data indicate that adverse effects on plants, invertebrates, birds, and mammals due to triclosan in land-applied biosolids are unlikely.
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