Presence of granuloma in Hodgkin lymphoma is a common finding which is often a source of diagnostic confusion.There is no clearly defined strategy to approach this dual pathology. The present case describes a diagnostic approach using modalities like immunohistochemistry and Catridge based nucleic acid amplification test that helped reach to most likely cause of granuloma with underlying Hodgkin lymphoma.
Isolated pleural effusion is a rare manifestation of filariasis that mimics tuberculosis, especially in endemic regions. We describe a case of lymphocytic and exudative pleural effusion showing microfilaria on pleural fluid cytology. A retrospective review of all cases of filarial pleural effusion reported after 2000 was conducted to evaluate the association between filariasis and pleural effusion as well as to screen the features that can help in accurate detection of these patients. The analysis suggested a causal association between the parasite and the development of pleural effusion with a high sensitivity of pleural fluid cytology for diagnosis.
Gastro-inestinal stromal tumours (GISTs) comprise 1–2% of all gastrointestinal (GI) tumours. The mesentery, retroperitoneum and omentum are common sites of extra-gastrointestinal stromal tumours (E-GISTs). Isolated involvement of the mesentery by tuberculosis (TB) without any evidence of pulmonary disease is quite unusual. Here we report a case of an E-GIST arising from the small bowel mesentery in a 60-year old female where an incidental concurrent mesenteric tuberculosis was diagnosed following surgical resection.
Background: Histoplasmosis is a mycotic infection commonly affecting patients with impaired immunity. It mainly manifests as pulmonary or disseminated infection. The diagnosis is often missed in non-endemic regions due to lack of suspicion especially when it involves unusual sites in healthy individuals.Case: An elderly male presented with solitary left shoulder swelling for the last 2 months. Clinical and radiological findings were suggestive of malignant etiology. Fine needle aspiration cytology from the lesion demonstrated yeast like fungi within the histiocytes. The cytomorphological features were suggestive of Histoplasma which was later confirmed on culture. Patients had an uneventful recovery with anti-fungal treatment.Conclusion: Histoplasma can present in elderly with indolent involvement of uncommon sites. High index of suspicion accompanied by active search using special stains is the key to diagnosis
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.