This paper presents the results of a large-scale, qualitative study conducted in the homes of children aged 7, 9, and 11 investigating Internet searching processes on Google. Seven search roles, representing distinct behavior patterns displayed by children when interacting with the Google search engine are described, including Developing Searchers, Domain-specific Searchers, Power Searchers, Non-motivated Searchers, Distracted Searchers, Rule-bound Searchers, and Visual Searchers. Other trends are described and selected to present a view of the whole child searcher. These roles and trends are used to make recommendations to designers, researchers, educators, and parents about the directions to take when considering how to best aid children to become search literate.

No abstract

Rituximab or immunoadsorption appeared to be promising preconditioning strategies before ABOi kidney transplantation. However, the overall quality of evidence and the confidence in the observed treatment effects are low. The increased use of ABOi kidney transplantation needs to be matched with randomized trials of different types, dosing, and frequency of preconditioning therapies so that this scarce resource can be used most effectively and efficiently.