IntroductionMortality from dengue infection is mostly due to shock. Among dengue patients with shock, approximately 30% have recurrent shock that requires a treatment change. Here, we report development of a clinical rule for use during a patient’s first shock episode to predict a recurrent shock episode.MethodsThe study was conducted in Center for Preventive Medicine in Vinh Long province and the Children’s Hospital No. 2 in Ho Chi Minh City, Vietnam. We included 444 dengue patients with shock, 126 of whom had recurrent shock (28%). Univariate and multivariate analyses and a preprocessing method were used to evaluate and select 14 clinical and laboratory signs recorded at shock onset. Five variables (admission day, purpura/ecchymosis, ascites/pleural effusion, blood platelet count and pulse pressure) were finally trained and validated by a 10-fold validation strategy with 10 times of repetition, using a logistic regression model.ResultsThe results showed that shorter admission day (fewer days prior to admission), purpura/ecchymosis, ascites/pleural effusion, low platelet count and narrow pulse pressure were independently associated with recurrent shock. Our logistic prediction model was capable of predicting recurrent shock when compared to the null method (P < 0.05) and was not outperformed by other prediction models. Our final scoring rule provided relatively good accuracy (AUC, 0.73; sensitivity and specificity, 68%). Score points derived from the logistic prediction model revealed identical accuracy with AUCs at 0.73. Using a cutoff value greater than −154.5, our simple scoring rule showed a sensitivity of 68.3% and a specificity of 68.2%.ConclusionsOur simple clinical rule is not to replace clinical judgment, but to help clinicians predict recurrent shock during a patient’s first dengue shock episode.

Oxindole derivatives were efficiently synthesized from diazoamides derived from aniline derivatives in the presence of a Ru(II)-Pheox catalyst. Ru(II)-Pheox was found to be one of the most efficient catalysts so far for the synthesis of oxindole derivatives from the diazoamides in high yields (up to 99%) with high regioselectivity. Furthermore, the reaction was rapid and no substituent effects on the aromatic ring.

Bài báo này trình bày một số kỹ thuật trong xử lý ảnh để nhận dạng ký tự đánh dấu (OMR), từ đó áp dụng để xây dựng ứng dụng nhận dạng hai loại phiếu khảo sát thường dùng tại Trường Đại học Đà Lạt. Chúng tôi sử dụng bộ thư viện Aforge để xây dựng ứng dụng minh hoạ. Kết quả thực nghiệm áp dụng cho hai loại phiếu là Khảo sát sinh viên về chất lượng giảng dạy và Khảo sát sinh viên về bộ phận hành chính sự nghiệp cho kết quả nhận dạng thành công 98,9% trên 667 phiếu thực nghiệm, thời gian nhận dạng nhanh gấp 9 lần so với việc nhập thủ công của nhân viên hành chính.

It is indisputable that developing pre-service teachers’ lesson-planning skills plays a key role in the language teacher training program. However, lesson planning is currently inadequately evaluated as a laborious task to many pre-service teachers, and they encounter a host of difficulties in tailoring a meticulous lesson plan. Since there is not much research into this subject in Vietnam, this paper is carried out with the purpose of investigating the difficulties in designing lesson plans experienced by pre-service teachers at the University of Foreign Language Studies – the University of Danang. This research employs qualitative approach of the data collected from questionnaire and semi-structured interview. The subject involves in the research are pre-service teachers majoring in English Language Teacher Education. Seventy (70) trainee teachers took part in the questionnaire at the first stage of data collection. Among these participants, at the second stage for semi-structured interview, the recording was administered to a population of ten (10) pre-service teachers who were chosen randomly with convenience. Hopefully, the research would serve as a source of reference for trainee teachers, in particular and teachers of English in general.