This report describes a monoclonal antibody designated G 250, subclass IgGl, that recognizes an antigen preferentially expressed on cell membranes of renal-cell carcinoma cells (RCC) and not expressed in normal proximal tubular epithelium. G 250 antibody reacted with 46 of 47 primary RCC, with 7 of 8 RCC metastases and with a few other malignant tumors. The staining pattern of G 250 differs from that of other RCC-related antibodies described. Preliminary experiments show that this antibody can be used to visualize RCC xenografts in nude mice by immunoscintigraphy.

No abstract

Islets of fully developed gastric mucosa i.e. containing parietal cells and sometimes pepsinogen cells were found in the duodenal cuff in 52 outof 158 gastric resection specimens. The gastric mucosa was seen significantly more often in the duodenum when the gastric resection was performed for duodenal ulceration. It is thought that the high acidity associatedwith the duodenal ulceration might be the cause forthe development of the heterotopic gastric mucosa.

No abstract

No abstract

Case 3-Dissection of the knee joint. Only minor degenerative changes. DEGENERATION OF JOINTS IN HAEMOPHILIACS UNDER TREATMENT BY MODERN METHODS 299 VOL.

No abstract

No abstract