A 44-year-old laser surgeon presented with laryngeal papillomatosis. In situ DNA hybridization of tissue from these tumors revealed human papillomavirus DNA types 6 and 11. Past history revealed that the surgeon had given laser therapy to patients with anogenital condylomas, which are known to harbor the same viral types. These findings suggest that the papillomas in our patient may have been caused by inhaled virus particles present in the laser plume.
Air-conduction and bone-conduction thresholds have both been determined in the conventional audiometric frequency ranges and in the extended high frequencies through respectively 18 and 16 kHz for otologically healthy subjects in different age groups covering the age span 8-14 years through the eighth decade. Subjects younger than 30 years had conventional frequency air-conduction thresholds < or = 10 dB HL, whereas the corresponding thresholds of older subjects were within 0.1 and 0.9 percentiles of ISO 7029 (1984). Age- and gender-specific thresholds, medians and ranges, are presented for bone conduction in the extended high frequencies. Thresholds increase with both age and frequency in the range 8-16 kHz, and there is a largely non-significant tendency for thresholds to be higher in males. Threshold deterioration at the highest frequencies is already present at age 18-24 years compared with the youngest (8-14 year) age group.
During a 9-year period a total of 447 peripheral facial palsies was seen. Of the 377 cases of acute idiopathic facial palsy (AIFP) for which information was available, 41 (10.9%) were recurrent attacks. The final outcome is known for 346 (92%) of AIFPs. All patients were subjected to an extensive investigation protocol. No prognostic differences were found between primary and recurrent attacks of AIFP and complete recovery occurred just as frequently after recurrent palsies irrespective of whether these were ipsilateral or contralateral to the first attack. The incidence of recurrent AIFP was 2.03/100,000/year.
1-10 years after the first examination, 56 children below 15 years of age with unilateral sensorineural hearing loss were re-examined with a test-battery consisting of puretone and speech audiometry, stapedius reflex tests, caloric tests, brainstem response audiometry and otoneurological tests. In no case was an acoustic tumour suspected on the basis of the test results. A small progression of the hearing loss occurred in only one ear. In no case did the healthy ears develop hearing loss during the observation period. Diagnostic procedures can in most of such cases be limited to pure-tone audiometry. Follow-up is indicated because some patients require advice considering education and evaluation regarding fitting of a hearing aid.
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