Our case series is limited by the absence of a control group and the retrospective analysis that was conducted. Large-scale prospective studies and pharmacovigilance monitoring are warranted to clarify the risks of VZV reactivation for all available SARS-CoV-2 vaccines. It should be determined whether all SARS-CoV-2 share a similar risk for this adverse reaction and should some of them be relatively safer in this regard, consideration should be given when choosing a vaccine for individuals most at risk for VZV reactivation (e.g. elderly, immunosuppression).

Intravitreal injections may lead to scleral changes when applied repeatedly in the same quadrant. Thus, alternating the injection site should be considered in patients requiring multiple intravitreal injections.

Superior continence rates were found for ROSC with an OBS compared with SC, without a negative impact on oncological outcome. ROSC should, therefore, be offered to women receiving an OBS whenever justifiable.

Wound products that reliably support healing of chronic leg ulcers remain a huge unmet need in clinical practice. Due to the lack of standardized comparable protocols and different systems for platelet-rich plasma (PRP) preparation, there is limited data on healing rates in chronic venous ulcers. In our case series with a total of seven chronic leg ulcers in four patients, we investigated the healing rates based on standardized digital photographs of chronic venous ulcers after application of topical PRP using a digital imaging software. In 5 out of 7 ulcers, the PRP-treated wound half showed faster healing as compared the control half of the wound. In this case series, PRP-treated sides of chronic venous leg ulcers showed a tendency for accelerated healing as compared to nontreated collateral wound side. Our data support the evaluation of topical PRP treatment in the management of chronic venous leg ulcers.