Background:LGBTQ is prone high prevalence and has economic, social business grow in wet and warm countries. It becomes political issue Worldwide (Time magazine, June 12, 2017, page Keywords-psycho-social, psycho forensic, biophysics, grey zone. CGG repeat, brain and behavior of LGBT.
Background: The kidneys are important organs in the human body that have many functions. Kidney function is divided into several processes, namely filtration, reabsorption and secretion of substances in the body. Nephron which is the smallest kidney functional unit that is responsible for accommodating all functions in the kidney. One of the functions of the kidneys is secretion, the secretions in the kidneys work by removing electrolytes and other substances that are no longer needed by the body through urine. When the function of the kidney nephrons is disturbed, it can result in an electrolyte imbalance (K), a buildup of waste from substances that are not needed by the body (creatinine). The objective of this research was to examine the relationship between electrolytes (K) serum, urine and creatinine in patients with CKD.Methods: The research was conducted by observational, anamnesis, and sampling of CKD patients at Dr. Kariadi Semarang during the period March-May 2020.Results: The results of the multivariate linear regression test showed that creatinine had a moderate significant positive effect at p = 0.024 and r = 0.412 on serum K. Meanwhile, from multivariate linear regression, it was found that creatinine had a moderate negative effect at p = 0.027 and r = -0.456 on urine K.Conclusions and suggestions: The findings proved the relationship between creatinine levels and serum and urine potassium levels in patients with CKD. Serum and urine electrolytes can be used as an parameter for CKD management.
Pendahuluan: Latar belakang: RNA untai ganda (dsRNA), siRNA, miRNA, RNAi, menginduksi metilasi DNA pada tumbuhan dan dalam sel mamalia, termasuk manusia. Kini RNAi menjadi prinsip dalam pengobatan kanker sekarang dan di masa depan. Masalah: Metilasi pulau CpG dan pengulangan DNA CGG merupakan kasus prevalensi tinggi di hutan hujan tropis, tetapi sampai sekarang terabaikan. Prinsip kehati-hatian dalam efek lingkungan harus diambil oleh para pembuat keputusan dan pemegang kebijakan. Tujuan: Mengetahui efek pembungkaman gen terhadap lingkungan. Hipotesis: RNAi menyebabkan hipermetilasi. Metode: Quasi ‘Systematic Review’ dengan Analisis Bayesian. Hasil: Menggunakan mesin pencari Science Direct, 935 referensi tertangkap ditambah 11 referensi yang sudah direkam dalam pustaka Mendeley, dan setelah menyaring abstrak atau judul, 920 dikeluarkan dengan duplikasi yang tidak relevan baik dianalisis dengan jaringan Bayesian terbaru untuk menjawab hipotesis. Menyaring teks lengkap dari 18, kemudian 16 teks lengkap dipilih. 28 teks lengkap diperiksa dan periksa kembali dengan meta-analisis RNA-metilasi menggunakan Science Direct (12 referensi). Diskusi: Sebuah teknik CpG-siRNA telah mempertahankan hipermetilasi pulau CpG, digunakan secara luas dalam terapi tanaman dan kanker untuk menstabilkan gen yang terbungkam.Kesimpulan: Pengaruh teknik pembungkaman gen terhadap lingkungan harus diketahui secara luas oleh pemegang kebijakan dan pengambil keputusan. Keywords: Hipermetilasi, Pulau CpG, RNAi, Pembungkaman gen, Budidaya ikan
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