A regular indium tin oxide (ITO) conductive network is fabricated by a simple "dipping and drying" process using cotton as a template. The flexible composite consists of an interconnected conductive network of ITO, which acts as a transport channel for charge carriers, and a poly(dimethyl siloxane) substrate. The composite shows a very high electrical conductivity of ∼5 S m −1 , which is ∼12 times of magnitude higher than those of other ordinary ITO-based composites. Moreover, it exhibits superior electrical/mechanical performance when bent or twisted compared to other ITO-based composites. The unique network structure and outstanding electrical, mechanical, and optical properties of the composite possess great potential for use in flexible, foldable, and stretchable electronics and other devices.
We report here the soft nanomaterial-based targeting polymersomes for near-infrared (NIR) fluorescence imaging to carry out in vivo tumor detection. Two polymersome-based NIR fluorescent probes were prepared through the self-assembly of amphiphilic block copolymers, poly(butadiene-b-ethylene oxide) (PEO-b-PBD). Each of them was encapsulated with distinct hydrophobic near-infrared dyes (DiD and DiR) and modified with different targeting ligands (anti-CEA antibody and anti-EGFR antibody), respectively. After simultaneous injection of these two probes into the tumor-bearing mice via tail vein, multispectral near-infrared fluorescence images were obtained. The results indicate that both probes are successfully directed to the tumor foci, where two distinguishable fluorescent signals were detected through the unmixed fluorescence images. By taking advantage of two targeting polymersome-based probes with distinct fluorescent features, the proposed multispectral near-infrared fluorescence imaging method can greatly improve the specificity and accuracy for in vivo tumor detection.
A novel ATO conductive network was prepared with a simple and versatile electrospinning process. The as-formed precursor samples are smooth and uniform with a length of several tens to hundreds of micrometers. After calcination, the precursor fibers were well-crystallized and the network morphology was well remained. The ATO network which constitutes the flexible composites with a poly(dimethyl siloxane) substrate is interconnected conductive and acts as a transport channel of charge carriers. The electrical conductivity of the composite is high to -3.4 S m(-1). Meanwhile it also can remain excellent performance when bent or twisted. The unique network structure and outstanding electrical, optical properties of the composite make it an ideal candidate for potential applications in flexible, foldable and stretchable electronics and other devices.
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