An unsupervised nuclei segmentation method for histology images is proposed in this work. It consists of three modules applied to each of non-overlapping blocks: 1) data-driven color transform for dimension reduction, 2) fully-automated adaptive binarization, and 3) incorporation of geometric priors with morphological processing. The method is called CBM, which comes from the first letter of the three modules -"Color transform", "Binarization" and "Morphological processing". Experiments on the MoNuSeg dataset validate the effectiveness of the proposed CBM method. It outperforms all other unsupervised methods and offers a competitive standing among supervised models based on the Aggregated Jaccard Index (AJI) metric.
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