The antihypertensive drug captopril was found to inhibit the oxidation of low density lipoproteins by copper in a dose dependent manner in vitro. Up to 65% inhibition of oxidation was observed at the concentration of 100 micrograms/ml of captopril. During subsequent studies with patients, captopril protected low density lipoproteins against oxidation slightly better than enalapril, although this difference was not statistically significant. Captopril had no effect on the levels of Lp(a) as compared to the levels established during enalapril treatment.
Two universities in Ottawa provide a full week of programs for bright secondary school students each spring. This study investigated factors which characterize the Mini-Course Enrichment Program as perceived by student participants and their parents. Findings were analyzed in terms of achievement, career aspirations and impact on self-image. Respondents perceived enhanced personal control, sense of risk-taking, and help in preparing for the future. Specific recommendations evolved for educators and administrators.
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