Introduction: Meningococcal disease (MD) is a public health problem worldwide, due to its high morbidity and mortality. Most cases occur in sub-Saharan Africa, where there is a marked seasonal pattern with predominance during the dry season. Objectives: To describe the morbidity of MD in the Metropolitan Region (MR) of Chile and explore whether there is a correlation between the number of cases with the levels of atmospheric particulate matter PM 10 and PM 2.5, relative humidity (RH), temperature and total environmental pollen. Materials and Methods: Ecological time series study, statistical analysis with R 3.0.1, graphics with Excel 2013. Results: Between 2010 and 2013, 234 MD cases were reported in the MR with an increasing trend. There is a seasonal pattern with an increase of cases from August to October, and a decrease from March to April. There is no correlation with the levels of PM10 and PM2.5. There is a slight positive correlation with RH and a slight negative correlation with temperature. There is a moderate positive correlation with the levels of total environmental pollens. Discussion: Overcrowding and the winter viral infections could explain the increased incidence of MD and the slight correlation with RH and temperature. The moderate correlation with the pollens could be explained by an effect of irritation of the upper airway. Conclusions: More epidemiological studies whose designs allow a greater causal inference are required.
The ESO Very Large Telescope Interferometer (VLTI) is the first general-user interferometer that offers nearand mid-infrared long-baseline interferometric observations in service and visitor mode to the whole astronomical community. Over the last two years, the VLTI has moved into its regular science operation mode with the two science instruments, MIDI and AMBER, both on all four 8 m Unit Telescopes and the first three 1.8 m Auxiliary Telescopes. We are currently devoting up to half of the available time for science, the rest is used for characterization and improvement of the existing system, plus additional installations. Since the first fringes with the VLTI on a star were obtained on March 17, 2001, there have been five years of scientific observations, with the different instruments, different telescopes and baselines. These observations have led so far to more than 40 refereed publications. We describe the current status of the VLTI and give an outlook for its near future.
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