Indblik-i-sundhedsvaesenets-resultater-maj-2016.pdf 3. Gamst-Jensen H, Lippert FK, Egerod I. Under-triage in telephone consultation is related to non-normative symptom description and interpersonal communication:A mixed methods study.
Results Baseline measurements were similar in both HS and TXA groups. Both groups showed a significant reduction in mean arterial pressure (MAP) after bleeding compared to baseline values, however at the end of the fluid resuscitation MAP was significantly higher in the TXA group (62.67±13.17 vs 92.20±22.35 mmHg, p<0.01). Echocardiographic stroke volume (SV) and left ventricle ejection fraction (LVEF) were higher in the TXA group at the end of both fluid resuscitation and blood transfusion phases (SV: 32.42±5.83 vs 45.23% ±13.76% and 35.11±14.62 vs 43.68%±13.92%, p not significant; LVEF: 65.9±5.3 vs 77.8%±4.7%, p=0.05 and 61.5 ±8.2 vs 76.3%±4.3%, p<0.01). No significant differences were observed in mixed venous saturation (SvO2) and lactate levels, despite SvO2 remained higher in the TXA group throughout the experiment except at baseline. Conclusion In this experimental model of HS the enteral administration of TXA was associated with a global improvement in hemodynamics; however, only small benefits were observed on mixed venous saturation and lactate levels.
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