Spindle cell soft tissue neoplasms are rarely reported in the oral cavity and account for less than 1% of all tumors. Spindle cell carcinoma (SpCC) synonymously called sarcomatoid tumor occurs mainly in the upper aerodigestive tract. This peculiar malignant neoplasm predominantly affects males in 6-7 th decades of life. SpCC is potentially aggressive with a high incidence of metastases. Its precise and early diagnosis is the key to good prognosis. We report a case of SpCC in a 50-year-old male patient with special reference to histogenesis of this entity. SpCC is an aggressive variant of squamous cell carcinoma which needs to be identified and differentiated from the other spindle cell tumors for proper treatment.
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