Motivated by the evidence that odontogenic keratocysts are associated with genetic alterations, we examined the possibility that development of other odontogenic cysts can be attributed to gene malfunctioning, in particular to the PTCH gene. Cyst epithelium was examined for polymorphism on chromosome 9q22.3, the region that contains the PTCH gene. Loss of heterozygosity (LOH) for the D9S287 marker and/or D9S180 marker was observed in about 50% of dentigerous cysts, whereas radicular cysts gave no indication of lesions in the PTCH region. As a more direct argument for PTCH involvement in cystic growth, we report evidence of PTCH expression in dentigerous cyst lining, which indicates malfunctioning of the relevant signaling pathway. While we found no reason to believe that PTCH should be associated with radicular cysts, other genes may be implicated in their development. We performed immunohistochemical comparisons of keratocysts, dentigerous and radicular cysts for the nonmetastatic marker Nm23. A graded response placed radicular cysts in between the other two types, suggesting a similar neoplastic character for their epithelial proliferation.
Although civilian populations have been heavily involved in most of the recent wars and conflicts throughout the world, most reports analyzed casualty data of military personnel, often leaving civilian casualties excluded or underestimated. A comparison of epidemiologic and medical data for maxillofacial injuries between civilians and servicemen (policemen, soldiers, and United Nations Protection Forces) during the aggression against Croatia is attempted. Of the 220 casualties admitted to the Department of Maxillofacial Surgery in Zagreb between August 1991 and December 1992, almost one-fourth were civilians. A significant difference between civilians and servicemen was noted in age and sex distribution. The incidence and severity of maxillofacial and associated injuries is almost equal, and the pattern of injuries is of the same type for civilian and military personnel.
U ovoj radionici predstavit ćemo teorijsku pozadinu kolagenog matriksa Mucograft te ćemo nakon toga pristupiti praktičnom vježbanju upotrebe istog na čeljusti svinje. Nakon predavanja polaznici radionice biti će upoznati s: • Osnovama i indikacijama za plastičnu oralnu kirurgiju • Tehnikama zbrinjavanja recesija na zubima i implantatima • Gingivnom i mukoznom augmentacijom koristeći vestibuloplastiku • Ograničenjima i rizicima kod korištenja transplantata mekog tkiva Praktična vježba uporabe Geistlich Mucograft umjesto autotransplantata: • Korištenje kolagenog matriksa Geistlich Mucograft • Tehnike režnjeva • Odizanje autotransplantata • Tehnike šivanja Pozivna predavanja
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