Glomeruli are histological structures of the kidney cortex formed by interwoven blood capillaries, and are responsible for blood filtration. Glomerular lesions impair kidney filtration capability, leading to protein loss and metabolic waste retention. An example of lesion is the glomerular hypercellularity, which is characterized by an increase in the number of cell nuclei in different areas of the glomeruli. Glomerular hypercellularity is a frequent lesion present in different kidney diseases. Automatic detection of glomerular hypercellularity would accelerate the screening of scanned histological slides for the lesion, enhancing clinical diagnosis. Having this in mind, we propose a new approach for classification of hypercellularity in human kidney images. Our proposed method introduces a novel architecture of a convolutional neural network (CNN) along with a support vector machine, achieving near perfect average results with the FIOCRUZ data set in a binary classification (lesion or normal). Our deepbased classifier outperformed the state-of-the-art results on the same data set.Additionally, classification of hypercellularity sub-lesions was also performed, considering mesangial, endocapilar and both lesions; in this multi-classification task, our proposed method just failed in 4% of the cases. To the best of our * First two authors contributed equally.knowledge, this is the first study on deep learning over a data set of glomerular hypercellularity images of human kidney.
Data charts are widely used in our daily lives, being present in regular media, such as newspapers, magazines, web pages, books, and many others. In general, a well-constructed data chart leads to an intuitive understanding of its underlying data. In the same way, when data charts have wrong design choices, a redesign of these representations might be needed. However, in most cases, these charts are shown as a static image, which means that the original data are not usually available. Therefore, automatic methods could be applied to extract the underlying data from the chart images to allow these changes. The task of recognizing charts and extracting data from them is complex, largely due to the variety of chart types and their visual characteristics. Other features in real-world images that can make this task difficult are photo distortions, noise, alignment, etc. Two computer vision techniques that can assist this task and have been little explored in this context are perspective detection and correction. These methods transform a distorted and noisy chart in a clear chart, with its type ready for data extraction or other uses. This paper proposes a classification, detection, and perspective correction process that is suitable for real-world usage, when considering the data used for training a state-of-the-art model for the extraction of a chart in real-world photography. The results showed that, with slight changes, chart recognition methods are now ready for real-world charts, when taking time and accuracy into consideration.
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