This study aimed to assess the reliability and agreement of automated head measurements using 3-dimensional (3D) photogrammetry in young children. Specifically, the study evaluated the agreement between manual and automated occipitofrontal circumference (OFC) measurements (n = 264) obtained from 3D images of 188 patients diagnosed with sagittal synostosis using a novel automated method proposed in this study. In addition, the study aimed to determine the interrater and intrarater reliability of the automatically extracted OFC, cephalic index, and volume. The results of the study showed that the automated OFC measurements had an excellent agreement with manual measurements, with a very strong regression score (R 2 = 0.969) and a small mean difference of −0.1 cm (−0.2%). The limits of agreement ranged from −0.93 to 0.74 cm, falling within the reported limits of agreement for manual OFC measurements. High interrater and intrarater reliability of OFC, cephalic index, and volume measurements were also demonstrated. The proposed method for automated OFC measurements was found to be a reliable alternative to manual measurements, which may be particularly beneficial in young children who undergo 3D imaging in craniofacial centers as part of their treatment protocol and in research settings that require a reproducible and transparent pipeline for anthropometric measurements. The method has been incorporated into CraniumPy, an open-source tool for 3D image visualization, registration, and optimization, which is publicly available on GitHub (https://github.com/T-AbdelAlim/CraniumPy).
Background: Significant discrepancies exist in the reported variables influencing alveolar bone graft outcomes. The purpose of this study was to evaluate graft success and identify outcome predictors in a large patient cohort using an objective Cone Beam Computed Tomographic (CBCT) assessment tool. Methods: Consecutive patients with cleft lip/palate who underwent alveolar bone grafting by one surgeon were included. Predictor variables were age at graft, oronasal fistula, canine position, concurrent premaxillary osteotomy, size of cleft, presence of bony palatal bridge, history of failed graft, location of primary repair, and surgeon experience. The outcome variable was graft success determined using a CBCT assessment tool and defined as a score of > 3 out of 4 in each domain: vertical bone level, labiopalatal thickness, and nasal piriform symmetry. Results: The sample included 900 alveolar cleft sites (median graft age 9.9 years). The success rate was 94.6%. Presence of an erupted canine, large cleft defect, and premaxillary osteotomy were independent predictors of graft failure, while presence of a bony palatal bridge was associated with graft success (p < 0.05). Conclusions: Presence of an erupted canine, large bony defect, and premaxillary osteotomy increase failure, and a bony palatal bridge portends success. Variables of age > 12 years, visible oronasal fistula, history of failed graft, primary cleft repaired at outside institution, and surgeon experience were associated with higher graft failure but were not independent predictors when controlling for co-variates. Surgeons should be aware that these factors in combination increase the odds of graft failure.
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