Background To evaluate the clinical and histopathological effects of natural extracts in the treatment of oral ulcers induced in animal experimental models. Material and Methods We carried out a search in the Medline, Scopus, WoS and Embase databases from the start of the databases to December 2020, and also made a manual search of the references. The search and selection were carried out by two researchers independently. The inclusion criteria were: experimental studies in animal models, in english, which complied with the study object. Results A total of 705 articles were identified. After selection by title, abstract and full text, 19 articles were finally included. Natural extracts of Jasminum grandiflorum , Ficus deltoidea , curcumin and Bixina orellana provoked a significantly greater reduction in the size of the ulcer. Extracts of Salvatora persica , Musa acuminate , Ganoderma lucidum mycelia and Bixina Orellana , as well as preparations of Kouyanqing Granule and curcumin, were able to reduce levels of pro-inflammatory cytokines and increase the expression and serum levels of growth factors and anti-inflammatory cytokines. Extracts of Piper sarmentosus , Cannabis sativa and Bletilla striata provoked a reduction in the severity of the histological inflammation. No significant differences were observed compared to controls in the treatments with extracts of Cannabis sativa , Aloe barbadensus Miller and Malva sylvestris in reducing the area of the oral ulcers. Conclusions Most of the natural extracts described in this review presented a positive clinical and histological effect on the cicatrisation of oral ulcers induced in animal models. Key words: Recurrent aphthous stomatitis, oral ulcer, plants, herbs, extracts, medicine, treatment.
The purpose of the study is to determine the necessity for a Dental English course in the dentistry degree program at the Universidad Autónoma de Chile. To achieve this objective, the target needs analysis instrument developed by Hutchinson and Water (1987) was adapted and distributed to 91 dentistry students and 35 of their teachers in order to determine the students' necessities, lacks, wants, expectations, preferred style of learning and teaching, and interest in the English for Dentistry course. For the quantitative data analysis, descriptive statistics were utilized, while thematic analysis was adopted for the qualitative data analysis. The results indicated the perceived importance of English is related to studying dentistry in their program and practicing dentistry in their future careers as dentists, the sense of lack is demonstrated in the inadequacy of English learning courses in their program curriculum as well as their current low level of English proficiency, and the need to focus on reading, writing, and vocabulary skills in order to write and read research articles in English. The study recommends implementation of a comprehensive branch of English language instruction that include English for General Purposes and English for Specific Purposes, such as English for Dentistry, English for Dental Consultation, and English for Writing Research Articles.
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