Objective
To investigate the role of topical negative pressure (TNP) therapy in the management of difficult wounds.
Design
Prospective consecutive patient series.
Patients and setting
30 patients referred to our tertiary plastic and reconstructive surgical service with wounds deemed unsuitable for reconstructive surgery were treated between November 1997 and the end of December 1998. The mean pretreatment duration of the wounds was 418 days (range, 8‐1650 days). All wounds were at least Grade Ill pressure sores.
Intervention
Topical negative presssure therapy (TNP) using the VAC device (KCI Medical, San Antonio, USA). Suction (75‐125mmHg) was continuous for the first 48 hours, then intermittent (2 min on, 5 min off).
Main outcome measures
Achievement of wound healing endpoints: (1) complete healing of the wound; (2) obliteration of the wound cavity to allow surface dressings; or (3) closure of the wound by suture or skin graft.
Results
TNP was successful in 26 out of 30 patients with mean therapy time of 35 days (range, 3‐124 days). Healing was more rapid in acute (less than six weeks old) wounds. A reduction in the number of bacterial species and colonies was also observed during therapy.
Conclusion
TNP can, in some circumstances, promote rapid secondary wound healing. A further randomised trial of TNP versus more traditional wound management modalities is justified.
This paper describes a simple method of classification and evaluation of the functional results of replanted and revascularized parts in the hand. The results are presented in graphic form and have been analyzed to correlate various factors: injured part, cause, and zone (level) of injury. The type of injury, ischemic time and age have been studied in more detail to determine their influence of the final functional result. The series contains 187 amputated and devascularized parts of the hand in 119 patients who have undergone surgery at the Prince of Wales Hospital from 1984 through 1988. The length of cold or warm ischemic times, up to 16 hours in this series, while not affecting survival of the amputated part, does adversely affect the functional result. The survival rate of replanted parts in children was significantly less favorable than in adults, but the functional results were uniformly superior.
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