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Parental participation is one of the cornerstones of paediatric practice. Evidence from the literature has shown that effective parental participation depends on parents’ preparedness, adequate communication between parents and nurses, and the negotiation process. However, little is known about the perception of these parents regarding their participation in the care of their hospitalised children. The aim of the study was to explore the perceptions of parents regarding their participation in the care of their children who were hospitalised at a government hospital in Malawi. A descriptive qualitative study was carried out using a semi-structured interview guide to collect data from 20 parents in the paediatric department. Thematic analysis was done guided by Colaizzi’s method. Three main themes emerged from the data and these were lack of role negotiation by healthcare workers, inadequate role preparation for parents, and parents’ perceptions of the care they provided to their hospitalised children. The study findings showed that parents view their participation in the care of hospitalised children as appropriate, important and satisfying. However, gaps exist in the way they participate in the care of their hospitalised children due to inadequate role negotiation and role preparation for parents and inadequate information from nurses. The researchers recommend that management should develop protocols and guidelines for the implementation of parental participation in the care of hospitalised children to promote best practices and quality children’s care.

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Tamoxifen is commonly prescribed for preventing recurrence in patients with breast cancer. However, the responses of the patients on tamoxifen treatment are variable. Cytochrome P450 genetic variants have been reported to have a significant impact on the clinical outcomes of tamoxifen treatment but no tangible conclusion can be made up till now. The present review attempts to provide a comprehensive review on the associative relationship between genetic polymorphisms in cytochrome P450 enzymes and survival in breast cancer patients on adjuvant tamoxifen therapy. The literature search was conducted using five databases, resulting in the inclusion of 58 studies in the review. An appraisal of the reporting quality of the included studies was conducted using the assessment tool from the Effective Public Health Practice Project (EPHPP). Meta-analyses were performed on CYP2D6 studies using Review Manager 5.3 software. For other studies, descriptive analyses were performed. The results of meta-analyses demonstrated that shorter overall survival, disease-free survival and relapse-free survival were found in the patients with decreased metabolisers when compared to normal metabolisers. The findings also showed that varying and conflicting results were reported by the included studies. The possible explanations for the variable results are discussed in this review.

Aims and ObjectivesTo explore the perceptions of family‐centred care among nurses and the family members of hospitalised children and investigate the facilitators of and barriers to the implementation of family‐centred care in Malawi.BackgroundIn Malawi, approximately 34% of children have long‐term illnesses that require hospitalisation. Family‐centred care ensures that the delivery of healthcare is grounded in partnerships between healthcare providers, patients and their families, which can improve the psychological well‐being of families. However, there is lack a good understanding of how families and nurses perceive this concept, its facilitators and the barriers.DesignThis was an exploratory qualitative study. Data were analysed deductively and inductively using the five‐step qualitative content analysis method.MethodsTwenty‐nine nurses and 31 families were recruited. Data were collected through in‐depth, semi‐structured and face‐to‐face individual interviews. The study was reported using the COREQ checklist.ResultsBoth nurses and families of hospitalised children recognised the importance of nurse–family partnerships in family‐centred care. Four themes emerged as follows: Perceptions of family‐centred care, elements of family‐centred care, facilitators of family‐centred care and barriers to family‐centred care. Specific information to families and the religious beliefs of families were identified as important facilitator and barrier to family‐centred care, respectively.ConclusionThe implementation of family‐centred care is promising in Malawi, as it is positively perceived by nurses and families, and its implementation is consistent with the Institute for Patient and Family‐Centred Care Framework.Relevance to clinical practiceOur findings present the best practices, gaps and challenges in the context of a low‐income country regrading implementation of family‐centred care. Education programmes on family‐centred care are crucial for sustaining the current gains.

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