The efficient conversion of optical laser light into bright ultrafast x-ray pulses in laser created plasmas is of high interest for dense plasma physics studies, material science, and other fields. However, the rapid hydrodynamic expansion that cools hot plasmas has limited the x-ray conversion efficiency (CE) to 1% or less. Here we demonstrate more than one order of magnitude increase in picosecond x-ray CE by tailoring near solid density plasmas to achieve a large radiative to hydrodynamic energy loss rate ratio, leading into a radiation loss dominated plasma regime. A record 20% CE into hν > 1 keV photons was measured in arrays of large aspect ratio Au nanowires heated to keV temperatures with ultrahigh contrast femtosecond laser pulses of relativistic intensity. The potential of these bright ultrafast x-ray point sources for table-top imaging is illustrated with single shot flash radiographs obtained using low laser pulse energy. These results will enable the deployment of brighter laser driven x-ray sources at both compact and large laser facilities.

For sparse samples or in the presence of ambient light, the signal-to-noise ratio (SNR) performance of single-pointscanning coherent anti-Stokes Raman scattering (CARS) images is not optimized. As an improvement, we propose replacing the conventional CARS focus-point illumination with a periodically structured focus line while continuing to collect the transmitted CARS intensity on a single detector. The object information along the illuminated line is obtained by numerically processing the CARS signal recorded for various periods of the structured focus line. We demonstrate experimentally the feasibility of this spatial frequency modulated imaging (SPIFI) in CARS (SPIFI-CARS) and SHG (SPIFI-SHG) and identify situations where its SNR is better than that of the single-point-scanning approach.

We report a line scanning imaging modality of compressive Raman technology with spatial frequency modulated illumination using a single pixel detector. We demonstrate the imaging and classification of three different chemical species at line scan rates of 40 Hz.

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imaging in the spatial frequency domain with a supercontinuum source," J.Abstract. We introduce a method for quantitative hyperspectral optical imaging in the spatial frequency domain (hs-SFDI) to image tissue absorption (μ a ) and reduced scattering (μ 0 s ) parameters over a broad spectral range. The hs-SFDI utilizes principles of spatial scanning of the spectrally dispersed output of a supercontinuum laser that is sinusoidally projected onto the tissue using a digital micromirror device. A scientific complementary metaloxide-semiconductor camera is used for capturing images that are demodulated and analyzed using SFDI computational models. The hs-SFDI performance is validated using tissue-simulating phantoms over a range of μ a and μ 0 s values. Quantitative hs-SFDI images are obtained from an ex-vivo beef sample to spatially resolve concentrations of oxy-, deoxy-, and met-hemoglobin, as well as water and fat fractions. Our results demonstrate that the hs-SFDI can quantitatively image tissue optical properties with 1000 spectral bins in the 580-to 950-nm range over a wide, scalable field of view. With an average accuracy of 6.7% and 12.3% in μ a and μ 0 s , respectively, compared to conventional methods, hs-SFDI offers a promising approach for quantitative hyperspectral tissue optical imaging.