A Síndrome Congênita do Zika Vírus é uma importante enfermidade que emergiu no Brasil no ano de 2015 e não existe cura para esta síndrome. O tratamento medicamentoso visa melhorar a qualidade de vida dos portadores desta doença; entretanto, a terapia medicamentosa com o uso de múltiplos fármacos pode acarretar efeitos adversos e interações medicamentosas. O objetivo do trabalho foi realizar o cuidado farmacêutico com os pacientes pediátricos portadores da Síndrome Congênita do Zika Vírus. Trata-se de um garanestudo longitudinal realizado na Clínica de Fisioterapia da Universidade Estadual da Paraíba e no Centro Especializado em Reabilitação, ambos localizados na cidade de Campina Grande, PB, durante 8 meses. Foram 5 atendimentos por pacientes pediátricos, um a cada mês, utilizando a metodologia Phamacoterapy WorKup e a base de dados Micromedex®. No total, foram avaliados 23 pacientes, 29 prescrições e 71 medicamentos pertencentes a 9 classes farmacológicas. Os anticonvulsivantes foram os mais prescritos. Quanto à comorbidade existente, 8 pacientes apresentaram duas ou mais doenças etiologicamente relacionadas. Houve 35 (49,2%) interações medicamento-medicamento, destas, 8 (22,9%) com efeito grave, 23 (65,7%) moderado, 4 (11,4%) menor e nenhuma contraindicada, além de 32 interações medicamentoalimento e 43 medicamento-laboratório. Os problemas relacionados aos medicamentos identificados foram 42; a ineficácia [23 (55%)] sendo o mais frequente. Portanto, é fundamental o acompanhamento farmacoterapêutico aos pacientes pediátricos portadores da Síndrome Congênita do Zika Vírus para avaliar o uso racional destes medicamentos, no qual o Cuidado Farmacêutico pode fazer a diferença na utilização segura e adequada dos fármacos.
The pursuit of quality of life, which has become marked in recent years, has translated into important population health benefits. This study assessed the quality of life of patients with type 2 diabetes (T2DM) who received pharmaceutical care, and their satisfaction with the service provided in community pharmacies. This single blind, randomized controlled clinical trial included 100 patients. The intervention group (N=47) received pharmaceutical care by a clinical pharmacist and the control group (N=42) received standard care. The Quality of Life Diabetes Questionnaire (DQOL) was used to measure all participants´ quality of life at study enrollment and six months later. Satisfaction of the participants in the intervention group was measured using a validated 14-items questionnaire. At the end of the study, participants in the intervention group had a statistically significant improvement in DQOL scores ( -0.62 x 1.57, p < 0.001) and were highly satisfied with the intervention (96% excellent satisfaction scores). Pharmaceutical care practice was associated with high satisfaction and increased quality of life scores in T2DM patients. These results underscore the important role of pharmacists to improve the health of diabetic patients.
objeCtives: To systematically identify and compare how generic medications, as defined by FDA, WHO, EMA, are classified and defined by regulatory agencies around the world. Methods: We focused on emerging markets and excluded developed countries. For country selection, we identified the 3 most populace countries in
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