ResultsThe average level of blood pressure in the day and night were signifi cant higher in the severe OSAS group (144.7/100.3 Ϯ 12.5/10.0mmHg, 136.5/91.1 Ϯ 13.3/9.5mmHg)than the pure hypertensive group (131.2/92.4 Ϯ 15.6/8.6mmHg, 124.9/84.7 Ϯ 18.3/11.7 mmHg, P Ͻ 0.05), while there were no signifi cant differences in light and moderate OSAS group. The variability of daytime blood pressure was signifi cant higher in the severe OSAS group (13.0/10.5 Ϯ 3.0/2.0 mmHg) than the pure hypertensive group (11.3/9.3 Ϯ 3.2/1.8 mmHg). The variability of nighttime blood pressure were signifi cant higher in the severe OSAS group (12.6/12.4 Ϯ 4.2/4.2 mmHg) than the pure hypertensive group (12.1/9.9 Ϯ 2.8/2.3 mmHg), the light OSAS group (11.3/10.0 Ϯ 2.8/3.0 mmHg), the moderate OSAS group (11.9/9.4 Ϯ 3.6/2.5 mmHg)(P Ͻ 0.05). Multiple regression analysis show that minSaO2 was an important factor affecting the nighttime and daytime blood pressure variability ( ϭ -0.103 P Ͻ 0.001; B ϭ -0.086, P Ͻ 0.003).
Conclus sSevere OSAS is correlated with hypertension and increase the variability of blood pressure. Hypoxia is an important factor for increasing the blood pressure variability in OSAS patients.
ConclusionsThere is a high prevalence of undiagnosed hypertension in patients with suspected sleep apnea syndrome. The BP and prevalence of hypertension is higher in SAS than in snorers without SAS. Only 1 of 3 patients with suspected SAS has a normal circadian BP rhythm.
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