Background: The aim of this study was to know the impact of the coronavirus disease 2019 (COVID-19) pandemic on Spanish patients with Parkinson's disease (PD). Methods: This is a descriptive, observational, crosssectional study. An anonymous online survey with 95 questions was distributed among patients. Responses were collected from 11 May 2020 to 20 July 2020. Results: Of a total of 570 questionnaires received, 568 (99.6%) were considered valid for the analysis (mean age, 63.5 ± 12.5 years; 53% females). A total of 553 patients (97.4%) were aware of the COVID-19 pandemic and 68.8% were concerned about it; 95.6% took preventive measures. A total of 484 patients (85.2%) had no contact with cases of COVID-19, and only 15 (2.6%) had confirmed COVID-19. Although up to 72.7% remained active during confinement, 65.7% perceived a worsening of their symptoms. Conclusions: Spanish patients with PD perceived the COVID-19 pandemic with concern and responsibility. More than half experienced worsening of their symptoms during confinement.

La pandemia del COVID19 ha generado un significativo impacto emocional en los pacientes institucionalizados por esta enfermedad, por el aislamiento, la incertidumbre, su propio estado de salud, generando diversas emergencias y urgencias psiquiátricas que ha tocado abordar. En ocasiones pacientes sin patología psiquiátrica previa o con medicación psicofarmacológica de larga data, ameritaran no solo intervención psicológica, sino además medicación, la cual debe ser indicada según la situación y teniendo en cuenta las interacciones con los fármacos experimentales que se están utilizando en estos pacientes. Palabras clave: COVID19, Infecciones por Coronavirus, Salud Mental, Efectos de los Fármacos, Coronavirus.