Se realizó un estudio exploratorio con el objetivo de comparar algunas propiedades químicas, físicas y biológicas de los suelos con cobertura en bosque de ladera (Bosque1), bosque en la vertiente del cauce de agua (Bosque2) y Pajonal, situados a similar altura, en la Reserva Natural Pueblo Viejo (Nariño). Se tomaron tres muestras de suelo por cada sitio, para un total de nueve muestras. Los datos, se procesaron mediante pruebas no paramétricas y Análisis de Componentes Principales. Se presentan diferencias estadísticas significativas entre Bosque2 y Pajonal, en C, N, CIC y Al, densidad aparente y densidad de Mollusca y, entre Bosque1 y Pajonal, en Mn y Cu. El análisis multivariado diferencia tres grupos correspondientes a los tres sitios.
Objective:
To investigate the anti-hyperglycemic effects of
Plathymenia reticulata
hydroalcoholic extract and related changes in body weight, lipid profile and the pancreas.
Methods:
Diabetes was induced in 75 adult male Wistar rats via oral gavage of 65mg/Kg of streptozotocin. Rats were allocated to one of 8 groups, as follows: diabetic and control rats treated with water, diabetic and control rats treated with 100mg/kg or 200mg/kg of plant extract, and diabetic and control rats treated with glyburide. Treatment consisted of oral gavage for 30 days. Blood glucose levels and body weight were measured weekly. Animals were sacrificed and lipid profile and pancreatic tissue samples analyzed. Statistical analysis consisted of ANOVA, post-hoc Tukey-Kramer, paired Student's
t
and
χ
2
tests; the level of significance was set at 5%.
Results:
Extract gavage at 100mg/kg led to a decrease in blood glucose levels in diabetic rats in the second, third (198.71±65.27
versus
428.00±15.25) and fourth weeks (253.29±47.37
versus
443.22±42.72), body weight loss (13.22±5.70
versus
109.60±9.95) and lower cholesterol levels (58.75±3.13
versus
80.11±4.01) in control rats. Extract gavage at 200mg/Kg led to a decrease in glucose levels on the fourth week in diabetic rats, body weight loss in the second, third and fourth weeks in control rats, and lower cholesterol levels in diabetic and control rats. Islet hyperplasia (p=0.005) and pancreatic duct dilation (p=0.047) were observed in diabetic and control rats.
Conclusion:
Plathymenia
extract reduced blood glucose levels in diabetic rats, and body weight in control rats, and promoted pancreatic islet hyperplasia in diabetic and control rats.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.