Electronic devices comprising a Langmuir−Blodgett molecular monolayer sandwiched between planar platinum and titanium metal electrodes functioned as switches and tunable resistors over a 102−105 Ω range under current or voltage control. Reversible hysteretic switching and resistance tuning was qualitatively similar for three very different molecular species, indicating a generic switching mechanism dominated by electrode properties or electrode/molecule interfaces, rather than molecule-specific behavior.

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The likelihood of discontinuing ChEI therapy was high in this real-world sample of AD patients. Significant predictors included clinical, socioeconomic, and practice factors.