The knowledge of antigens of erythrocyte blood groups enabled better transfusion management with a reduction in transfusion accidents. In recent years, progress has been made in the discovery and characterization of platelet antigens and the search for antiplatelet antibodies which also improve the management of patients in neonatology, transfusion therapy and organ transplantation. Unfortunately in Africa, few studies on the distribution of the frequency of platelet antigens are available. Given limited resources, our work aims to have a distribution of the frequency of platelet antigens of the HPA-1 system in the population in the Ivory Coast. The phenotyping of the antigens of the HPA-1 system was carried out on each tube of citrated blood collected by the MAIPA method (Monoclonal Antibody-Specific Immobilization Platelet Antigen). 184 blood donors with a male predominance were included and the results obtained during our work report a predominance of HPA-1a antigens with 99.46% versus 0.54% for HPA-1b antigens. To the best of our knowledge, there are no data available in Ivory Coast .Therefore, this work will allow us to establish a distribution of the platelet antigen polymorphism of the HPA-1 system of the Ivorian population and to demonstrate the need to implement measures to control the prevalence of immunizations related to platelets.
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