Traditional remedies are gaining worldwide acceptability. In the developing country like India safe, efficient and economic indigenous remedies are gaining popularity among the urban and rural areas. Diabetes is one of the major lifestyle disease which remains without a promising management solution in conventional medicine. In Ayurveda, this disease can be largely equated to a disease process called Prameha. The Western Ghats consists of unusual flora of Sahyadri hills representing dense and diversified vegetation. The people here are largely dependent on the available natural resources for food and medicine at primary level in treatment of diabetes. Not much work has been done so far for exploration of anti diabetic activity of these medicinal plants in correlation with its mode of action in perspective of Ayurveda texts and modern literature collectively. So the paper will highlight the anti diabetic potential of some selected medicinal plants used here for diabetic treatment through available Ayurveda literature and recent researches done so far.
Ayurveda is the ancient science of medicine in the world; its legacy goes back to the Vedic era. Ayurveda has a unique holistic approach towards life, health, and cure. It has two main aims -one is to maintain good health and the second is to cure diseases. The Rasayana or rejuvenation is one of the eight specialized branches of Ayurveda that primarily deals with the maintenance of health. The focal basis of Rasayana is accelerated and appropriate nutrition to improve the biological competence of body. A good intellectual power acts as a catalyst in all aspects of life. All Rasayanas are nutrition promoters in general but there is certain target specific Rasayanas viz. Medhya Rasayana for the brain, Hridya Rasayana for the heart, Caksusya Rasayana for eyes and so on. Medhya Rasayana is claimed to promote cognitive functions of the brain and helps in regeneration of neural tissues besides producing antistress, adaptogenic and memory enhancing effect, and retarding brain aging. Four Medhya Rasayana are mentioned in the 1 st chapter of Charak Samhita. Acharya Charaka used Swarasa (fresh juice) of Mandukaparni leaves, Churna (powder) of Yasthimadhu root & stolon along with milk, extract of Guduchi stem and paste of the whole plant of Shankhapuspi. All these drugs have multi-dimensional actions having an influence on mental health. They not only enhance the Dhi (Power of acquisition), Dhriti (power of retention), Smriti (power of recollection) but also rejuvenate the whole system and their pathways.
Karushkara Lata (Strychnos colubrine L.) commonly called as Snakewood Plant is wildly distributed throughout Western ghats of India. It is an important medicinal plant of genus Strychnos. There are traditional claims for usefulness of the plant as an antidote to snakebite, as a febrifuge, anthelmintic, in cutaneous infection and to check diarrhea. The major chemical constituent includes strychnine and brucine but very few researches have been conducted so far regarding its pharmacological activities. In Ayurveda system of medicine, the plant is mentioned a bitter tonic having krimighna, jwaraghna and twakadoshahara action. So the present review aims to explore the significance of this plant giving a scope for further scientific research.
During the last few years India has maximum increase of Type 2 diabetes mellitus. Type 2 diabetes is characterized by high blood sugar, insulin resistance, and relative lack of insulin. There are approximate 72.96 million cases of diabetes mellitus in adult population of India. In modern era single anti-diabetic drug is not sufficient for glucose control. These days multidrug therapy is building its popularity for maintaining glycaemic levels. A 59-year-old female presented with known case of Type 2 diabetes with evidence of polyuria, itching over extremities, and fatigue was poorly controlled despite a drug regimen consisting of oral metformin and glimepiride. Her Blood Sugar level was constantly around 200 mg/dl in spite of having modern medicine with adjusted doses. She has administered Nisha-Amalaki Churna with warm water early in the morning along with standard conventional treatment for 8 weeks. The effect of therapy was evaluated at the interval of 4 weeks for 8 weeks which is done on the basis of objective parameters. Objective parameters were fasting and post prandial Blood Sugar Level. Nisha-Amalaki churna has reduced Blood Sugar Level to normal. It also reduced the dose of conventional drug which may cause side effects with long term use. There is a need for combined multidisciplinary treatment to maintain suggested glycaemic control. Thus, the present case study is to understand the significant effect of Nisha-Amalaki as an adjuvant to standard conventional treatment in chronic uncontrolled type 2 Diabetes Mellitus.
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