Introduction: Post-pericardiotomy syndrome is a relatively common complication after open heart surgery. In recent years, colchicine had a good effect on treatment of the pericarditis. Objectives: This study aimed to study the effect of colchicine to prevent post-pericardiotomy syndrome in patients who had open heart surgery. Patients and Methods: This double-blind clinical trial study was conducted on 240 patients undergone open heart surgery. Eligible patients were selected by simple sampling and randomly divided into two groups; 120 subjects in the experimental group receive colchicine (1 mg for patients greater than 70 kg and 0.5 mg for patients lower than 70 kg) and 120 subjects in the control group who received the placebo. Patients were followed up regarding the incidence of post-pericardiotomy syndrome after the surgery during hospitalization and in follow up visits in one month and six months after hospital discharges. Results: In total, the incidence rate of post-pericardiotomy syndrome was 33.7% (81 subjects). A significant difference of post-pericardiotomy syndrome between two groups was seen. We found post-pericardiotomy syndrome in 12.1% (29 patients) of colchicine group versus 21.6% (52 patients) in the placebo group (chi-square test). The incidence rate based on the Kaplan-Meier curve, in the second week to one month after the surgery, was lower in colchicine group while in third to the sixth month it had a constant trend. Conclusion: Colchicine is effective for prevention the post-pericardiotomy syndrome without any life-threatening complication.
IntroductionPregnancy is one of the most critical periods of women life which can make physical, mental and behavioral changes. These physical and psychological changes may also lead to changes in sexual and marital relations of couples (1, 2). Conflicts and challenges of couples associated with pregnancy and multiple physical and psychological changes during pregnancy reduce quality of the sexual relation (3, 4). During pregnancy and even months after childbirth, desire for sexual activity decreases and rate of sexual dysfunctions compared to pre-pregnancy increases. This can cause emergence of considerable turmoil in relations between spouses (5). Couple's relationship quality during pregnancy is largely influenced by their sexual relations and specific set of beliefs and opinions that have been exist around the world which know no borders (6). As the pregnant women report lower levels of sexual desire and sexual intimacy comparing with non-pregnant women (3), stressful physical, emotional and financial factors resulting from pregnancy may have a negative effect on the emotional and sexual intimacy. Attitudes and sexual behaviors during pregnancy are affected by sexual value systems, indigenous culture, traditional and religious beliefs (7). Some of the beliefs such as change of mental image of one's own body (body image), discarding the sexual activity and feeling guilty about sexual relations during pregnancy, decreased feeling about being attractive to the husband, fear of harming the fetus, fear of miscarriage and preterm delivery, etc may have negative effect on the individual sexual response and finally on the relationship of couples, that it cause anxiety and lack of confidence of them (8-10).About 86% to 100% of couples keep their sexual activity during pregnancy; most of women show decreased sexual desire and frequency of sexual intercourse as the pregnancy is progressed (11). Although sexual desire, performance and satisfaction of pregnant women and husbands are unpredictable and may increase, decrease or remain unchanged during pregnancy (7,12), Fok et al showed that more than 60% of women and 40% of their spouse experienced decrease sexual desire and arousal during pregnancy, and more than 80% of women and their spouse were concerned about harmfulness of sexual activity on the fetus (13).Although continued sexual activity during pregnancy, without proper principles, lead to complications for mother and fetus, medical science has not placed restrictions on sexual activity in a healthy pregnancy and the balanced sexual relationship can be continued during pregnancy apart from high-risk groups (14). Results of meta-analy- AbstractObjectives: Sexual activity is one of the most important issues in life. Sex during pregnancy can fluctuate according to physical and psychological changes. This study aimed to examine the effect of sex group counseling on sexual response of pregnant women. Materials and Methods:This study is a quasi-experimental intervention. Among pregnant women of Zahedan who were referred...
Background: Enuresis has been defined as bed voiding at least twice a week for more than 3 consecutive months in individuals older than 5 years of age. Increased nocturnal enuresis could be possibly associated with dysfunction of autonomic nervous system. To observe autonomic nervous system function in enuretic children, the current study performed management of blood pressure. Methods: In this study, primary non-monosymptomatic nocturnal enuresis and healthy children were enrolled and blood pressure was measured twice, in the morning and afternoon. Urinalysis, urine culture, and urinary system ultrasound were carried out for the patients. A diary on the daily fluid intake and volume of daily urine was required. Results: The researchers observed that there was a significant difference between age variation (P value = 0.001) gender variation (P value = 0.030), educational level of patients' mothers and fathers (P value = 0.001) and record of hypertension in the family (P value = 0.001) between case and control groups. Conclusions: In children affected by primary non-monosymptomatic nocturnal enuresis, nighttime Systolic Blood Pressure (SBP) were significantly higher, than healthy children. These circadian blood pressure provisions may reflect pathogenesis of primary non-monosymptomatic nocturnal enuresis and autonomic nervous system dysfunction.
BackgroundMarital relationships may fluctuate due to physical and psychological changes during pregnancy. This study aimed to investigate the effect of group sexual counseling on the traditional perceptions and attitudes of pregnant women.MethodsThis was a quasiexperimental intervention study. Among the pregnant women who were referred to health care centers in Zahedan, Iran, in 2015 for routine care during pregnancy, 100 individuals were chosen and randomly categorized into two groups: intervention (n=50) and control (n=50). Variables were the participant’s attitudes and beliefs on sexual activity during pregnancy. The data were collected during pregnancy using the Sexual Activities and Attitudes Questionnaire. The questionnaire was completed before and 6 weeks after five sessions of group sexual counseling. Data were analyzed using SPSS software (Version 20) with descriptive and analytical statistics.ResultsThe mean of score changes for sexual attitudes and traditional perceptions in the intervention group was significantly higher than that in the control group (P<0.0001). Analysis of covariance also showed that the mean score of the participant’s traditional perceptions and sexual attitudes in both groups was significantly different after the group sexual counseling.DiscussionDue to the positive effect of group sexual counseling on improving the attitudes of pregnant women about sexual issues and reframing the traditional perceptions over sexual activities during pregnancy, it is recommended that this educational intervention should be integrated into counseling and prenatal care for pregnant women.
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