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The pipelines of approaches for classifying diabetic retinopathy were examined in this study. The effort entails developing appropriate transformations and estimators that can be used to automate the process of diabetic retinopathy detection. The segmentation of the blood vessels was done using a hybrid algorithm that uses Otsu and median filter to get the region of interest. Further, ten classifiers were investigated in order to develop an automated pipeline for diabetic retinopathy detection. The ten classifiers were reviewed based on earlier work in a similar setting and on an exploration of new ways for identifying diabetic retinopathy. To overcome the challenge of low volume of dataset, data argumentation was done so that a generic classifier can be configured. Extensive hyper parameter tuning was performed, and it was shown that the gradient boosting approach is the most stable technique for detecting diabetic retinopathy. This was validated using a 10K fold cross validation method on many metrics (accuracy, recall, precision, and v-measure score). Hyper-parameter tuning helped in achieving accuracy of 0.96.

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The detection of eye illnesses requires a thorough inspection of all of the eye's structures. Most significantly, the presence of blood vessels, an optical disc, and any other unwelcome objects, if any are discovered, is critical in determining the type of eye disease present. Specifically, the goal of this research is to establish a thorough segmentation framework that will aid in the detection of anatomical anomalies in the eye. A novel segmentation technique for analyzing blood vessels, optical disc health, and the presence of exudates has been added into the software. - It was decided to add the detection of aberrant objects such as exudates into the algorithm in order to develop a generic segmentation method. In order to verify the accuracy of the segmentation at each stage, random sampling is employed at each stage. The segmentation is then validated using the intersection over union metric. The accuracy of the integrated segmentation method as a whole is 91.66 percent.

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