Idiopathic scrotal calcinosis (ISC) is a rare benign disorder of scrotal skin which presents with multiple, asymptomatic nodules on the scrotum. In this text, we report a 44-year old man, who admitted to urology department outpatient clinic with a history of multiple, painless, firm swellings on his scrotum for about twenty year. After excision of the nodules under local anesthesia histopathologic examination was performed. Typical histologic features of idiopathic scrotal calcinosis were observed. Since few cases have been reported in the literature, herein we present a case of idiopathic scrotal calcinosis and a short review of the literature. Key words: Scrotum, calcinosisİdiopatik skrotal kalsinozis (İSK) skrotum derisinde birden çok sayıda asemptomatik nodül oluşumuyla karakterize nadir görülen benign bir hastalıktır. Skrotum derisinde yaklaşık yirmi yıldır çok sayıda, ağrısız, sert nodülleri olan bir hastanın lezyonları lokal anestezi ile eksize edildi ve histopatolojik olarak İSK tanısı konuldu. Bu çalışmada nadir görülen bir hastalık olan İSK literatür eşliğinde sunulmuştur.Anahtar sözcükler: Skrotum, kalsinozis I diopathic scrotal calcinosis (ISC) is a rare benign disease of scrotal skin, which presents with multiple, asymptomatic nodules on the scrotum appearing in childhood or early adulthood (1). The main controversy is about the etiology of the entity, whether it is idiopathic or occurs due to a proceeding systemic or metabolic disorder (1). Because of its rarity and controversial nature of its development, we present a case of ISC in this report. Case reportA 44-year-old man was referred to the outpatient clinic of urology with a twenty year history of painless subcutaneous nodules on the scrotum. Physical examination revealed about twenty-three painless, well-circumscribed subcutaneous nodules in varying diameters on the scrotum (Fig.1). There was no history of systemic, metabolic, endocrinologic, neoplastic or autoimmune diseases, scrotal trauma or inflammatory disorder of scrotum. Routine laboratory examinations, including serum calcium, phosphorus and parathyroid hormone showed no abnormality. The nodules were extirpated surgically under local anaesthesia and the patient's postoperative course was uneventful. The cut surfaces of the nodules were in a yellowish-whitish, chalky appearance macroscopically. Histopathologic examination under light microscopy revealed amorphous calcified areas located in the dermis. Extensive fibrotic areas and foreign body reactions were also present within the lesions. No epithelial lining was noted (Fig. 2).