BACKGROUND Stroke is disastrous particularly in young due to its immediate and long-term impact on victims, burden on their families and at large on the society. As the incidence of young stroke is increasing, we aimed to find out aetiology, clinical profile and risk factors of young stroke at Maharaja Yeshwant Rao Hospital, Central India. METHODS The present descriptive and clinical study was carried out in the Department of Medicine, M.G.M. Medical College and Maharaja Yeshwant Rao Hospital, Indore from Oct. 2013 to Oct. 2014 after approval from Institutional Ethics Committee. A total of 50 consecutive patients between 18-45 years of age presenting with stroke were recruited who were fulfilling inclusion criteria and exclusion criteria after taking prior informed consent. RESULTS Males (59%) were more commonly affected than females. Mean age of study population was 31.70±7.42 years and that of male and female patients was 33.03±7.131 and 29.85±7.237 years respectively and majority of stroke patients were in the age group of 36-40 years (26%). Motor deficit (90%) was most common clinical presentation. 78% patients suffered ischemic stroke. Most common aetiological factors were atherosclerosis (28%), smoking (40%), alcohol (32%) and hypertension (32%). CONCLUSIONS Smoking and alcohol are two leading modifiable risk factors found in our study, suggesting that increased public awareness and public health system interventions could reduce overall burden due to young stroke.
Background: Migraine is characterized by recurrent attacks of disabling headache and autonomic nervous system dysfunction. Up to one third of patients also have neurological aura symptoms. It has been suggested that migraine can be a risk factor for stroke. Migraine affects three times the number of women than men. The incidence of stroke in men is two times that of women. It is shown in several studies that women aged 35 to 45 years old are at increased risk of ischemic stroke who had migraine with or without aura.Methods: The present cross sectional study was conducted in 350 consecutive patients of stroke who were attended OPD and admitted in wards of the Department of Medicine, M.G.M. Medical College and MY Hospital, Indore, MP, India, during period from December 2017 to December 2018.Results: The highest percentage of respondents i.e. 68% belonged to male group followed by 32% of respondents who were females. The highest percentage of respondents i.e. 66.6% had ischemic stroke while, 33.4% had hemorrhagic stroke. The highest percentage of respondents i.e. 90.9% had no Migraine while, 9.1% had Migraine. The highest percentage of respondents i.e. 31.2% had weekly reoccurrence, followed by forth nightly (25%) and lowest was 3.1% of daily recurrence. The association of type of stroke with sex group of patient’s history of headache which found to be significant (p ˂0.05). The association of type of stroke with sex group of patient’s history of various cerebro-vascular risk factors which found to be significant (p<0.05). Patients having hemorrhagic and ischemic stroke also had HTN in 47% and 12.4% patients respectively.Conclusions: In this study it is concluded that migraine can be established as a risk factor for ischemic stroke. Early diagnosis and treatment with available medication can be helpful in prevention or decreasing risk for developing stroke.
Background: Diabetes Mellitus is one of the prevalent metabolic disease which is associate with dyslipidemia. This poses this patient for signicantly increased cardiovascular risk events like stroke, myocardial infarction etc. Statins are widely used among these patients for primary prevention of cardiovascular risk. This study emphasizes on pattern of statin therapy being practiced in Indian setup and lacunae related to with aspect of improving public health Methods: This study was a crossectional observational study conducted in a tertiary care teaching hospital of central India. The study was started after obtaining clearance from Institute Ethics Committee. The patients satisfying the inclusion criteria were recruited in this study after obtaining Informed consent. The diabetic patients were assessed for statin therapy and intensity of statin therapy widely prescribed and practiced with respect to Indian population. Results: Of total 2680 diabetic patients recruited in this study, 1800 (67.16%) were prescribed with statin therapy, of which 41.5% were males and 25.66% were females. 1280 diabetic patients were prescribed with Atorvastatin and 520 were prescribed with Rosuvastatin.Of all the available statins, Two statins, Atorvastatin and Rosuvastatin, was prescribed to the diabetic patients the most. Conclusion: This study will be providing baseline data regarding drug utilization pattern of statins in diabetic patients. This study will help in assessing the statin eligibility and to determine data pertaining to overuse or underuse of statins in diabetic patients. It also emphasizes the pattern of statin being prescribed based on its intensity. The data of this study will be useful to plan further research related cardiovascular risk and statin considering various factors for Indian population
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